Palivizumab prophylaxis of respiratory syncytial virus infection in high-risk infants

被引:24
|
作者
Vogel, AM
Lennon, DR
Broadbent, R
Byrnes, CA
Grimwood, K
Mildenhall, L
Richardson, V
Rowley, S
机构
[1] Univ Auckland, Wellington, New Zealand
[2] Paediat Soc New Zealand, Infect Dis & Immunisat Comm, Wellington, New Zealand
[3] Paediat Soc New Zealand, Fetus & Newborn Comm, Wellington, New Zealand
[4] Paediat Soc New Zealand, Resp Comm, Wellington, New Zealand
关键词
consensus; cost effectiveness; palivizumab; preterm; respiratory syncytial virus;
D O I
10.1046/j.1440-1754.2002.00057.x
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
Palivizumab prophylaxis significantly reduces hospitalization for respiratory syncytial virus (RSV) disease in preterm infants. However, palivizumab is very expensive. Data from a New Zealand cost-effectiveness analysis were considered by representatives of the Infectious Diseases and Immunisation, Fetus and Newborn, and Respiratory Committees of the Paediatric Society of New Zealand. Prophylaxis in all high-risk groups was associated with net cost. The consensus panel recommends that the priority for palivizumab be given to babies discharged on home oxygen with chronic lung disease, followed by babies born at 28 weeks or less gestation.
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页码:550 / 554
页数:5
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