Dolominol a and B, two new neolignans from Dolomiaea souliei (Franch.) C.Shih

被引：2
|
作者：
Yi, Man [1 ]
Meng, Fan-Cheng [1 ]
Qu, Shen-Yue [1 ]
Mao, Jing-Xin [1 ]
Wang, Guowei [1 ]
Liu, Mingxing [1 ]
Liao, Zhi-Hua [2 ]
Chen, Min [1 ]
机构：
[1] Southwest Univ, Coll Pharmaceut Sci, Chongqing, Peoples R China
[2] Southwest Univ, Sch Life Sci, Chongqing, Peoples R China
来源：
NATURAL PRODUCT RESEARCH | 2022年 / 36卷 / 15期
基金：
中国博士后科学基金;
关键词：
Dolomiaea souliei (Franch.) C.Shih; neolignans; dolominol A; dolominol B; hepatoprotective effect;
D O I：
10.1080/14786419.2021.1897125
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
Two new neolignans, dolominol A (1) and dolominol B (2), together with 12 known lignans, erythro-(7S,8R)-guaiacyl-glycerol-beta-O-4 '-dihydroconiferyl ether (3), threo-(7R, 8R)-1- (4- hydroxy- 3- methoxyphenyl) - 2-{4-[(E)- 3- hydroxy- 1- propen yl) ]- 2- methoxyphenoxy}-1, 3- propanediol (4), (-)-dihydrodehydrodiconiferyl alcohol (5), (-)-massoniresinol (6), vladinol D (7), syringaresinol (8), prinsepiol (9), medioresinol (10), (+)-pinoresinol (11), 2 alpha-guaicyl-4-oxo-6 alpha-catechyl-3,7-dioxabicyclo [3.3.0]octane (12), cycloolivil (13), isolariciresinol (14) were isolated from Dolomiaea souliei (Franch.) C.Shih. Their structures were determined by UV, CD, HR-ESI-TOFMS, 1 D and 2 D NMR experiments. Their hepatoprotective effect against LPS-induced L-02 cells injury was also studied. Result revealed that compound 4 showed best protective effect on LPS-induced L-02 cells. [GRAPHICS] .
引用
下载
收藏
页码：3909 / 3916
页数：8
相关论文
共 50 条
  • [1] New acetylenic compounds and lignans from Dolomiaea berardioidea (Franch.) Shih
    Huang, Ying-Ying
    Qiu, Xin
    Xie, Yang-Guo
    Wu, Guo-Jing
    Zhu, Sheng-Lan
    Zhang, Wei-Dong
    Zhang, Yan
    Dai-Jie, Chen
    Jin, Hui-Zi
    PHYTOCHEMISTRY LETTERS, 2019, 31 : 125 - 130
  • [2] Two New Aryltetralin Lignans from the Roots of Dolomiaea souliei
    Wei, Hua
    He, Chunnian
    Peng, Yong
    Zhang, Sen
    Chen, Xiaoguang
    Xiao, Peigen
    MOLECULES, 2012, 17 (05): : 5544 - 5549
  • [3] Two new C19-diterpenoid alkaloids from Delphinium davidii Franch.
    Liang, Xiao Xia
    Chen, Dong Lin
    Wang, Feng Peng
    CHINESE CHEMICAL LETTERS, 2006, 17 (11) : 1473 - 1476
  • [4] Two new complex triterpenoid saponins from Gledistsia dolavayi Franch.
    Teng, RW
    Ni, W
    Wang, DZ
    Ding, JK
    Chen, CX
    MAGNETIC RESONANCE IN CHEMISTRY, 2002, 40 (09) : 609 - 613
  • [5] Two New Spirostanol Glycosides from the Roots and Rhizomes of Helleborus thibetanus Franch.
    Li, Yuze
    Zhang, Zilong
    Huang, Wenli
    Zhang, Huawei
    Jiang, Yi
    Liu, Jianli
    Song, Xiaomei
    Zhang, Dongdong
    RECORDS OF NATURAL PRODUCTS, 2023, 17 (02) : 318 - 328
  • [6] Rigenolides B and C, conjugates of norsecoiridoid and secoiridoid glucoside from Gentiana rigescens Franch.
    Suyama, Yoshihiro
    Tanaka, Naonobu
    Kawazoe, Kazuyoshi
    Murakami, Kotaro
    Li, Shun-Lin
    Sun, Han-Dong
    Kashiwada, Yoshiki
    TETRAHEDRON LETTERS, 2017, 58 (15) : 1459 - 1461
  • [7] Souline C and souline D, two new diterpenoid alkaloids from Delphinium souliei
    Zhang, K
    He, L
    Pan, XA
    Chen, YZ
    PLANTA MEDICA, 1998, 64 (06) : 580 - 581
  • [8] ASTERYUNNANOSIDE　A　AND　B，TWO　NEW　TRITERPENOID　SAPONINS　FROM　ASTER　YUNNANENSIS　FRANCH
    Yu SHAO
    Jin Hai GAO and Bing Nan ZHOU(State Key Laboratory of New Drug Research Shanghai Institute of Materia Medica.Academia Sinica Shanghai 200031)
    Chinese Chemical Letters, 1994, (02) : 121 - 124
  • [9] Madangones A and B: Two new neolignans from the stem bark of Beilschmiedia madang and their bioactivities
    Salleh, Wan Mohd Nuzul Hakimi Wan
    Ahmad, Farediah
    Yen, Khong Heng
    Zulkifli, Razauden Mohamed
    Sarker, Satyajit Dey
    PHYTOCHEMISTRY LETTERS, 2016, 15 : 168 - 173
  • [10] Two New O- and C-glycosyxanthones from the Gentiana tizuensis Franch
    Tian, Xuan
    Xu, XiuZhi
    Zhan, Huiying
    Wang, Aili
    CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE, 2001, 22 : 148 - 150
12345