When MARCH family proteins meet viral infections

被引：13
|
作者：
Zheng, Chunfu [1 ,3 ]
Tang, Yan-Dong [2 ]
机构：
[1] Fujian Med Univ, Sch Basic Med Sci, Dept Immunol, Fuzhou, Peoples R China
[2] Chinese Acad Agr Sci, State Key Lab Vet Biotechnol, Harbin Vet Res Inst, Harbin, Peoples R China
[3] Univ Calgary, Dept Microbiol Immunol & Infect Dis, Calgary, AB, Canada
来源：
VIROLOGY JOURNAL | 2021年 / 18卷 / 01期
关键词：
MARCH; Antiviral; Proviral; RING finger; E3; ligase; E3 UBIQUITIN LIGASE; HIV-1; INFECTION; EXPRESSION;
D O I：
10.1186/s12985-021-01520-4
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
Membrane-associated RING-CH (MARCH) ubiquitin ligases belong to a RING finger domain E3 ligases family. Recent studies have demonstrated that MARCH proteins play critical roles during various viral infections. MARCH proteins can directly antagonize different steps of the viral life cycle and promote individual viral infection. This mini-review will focus on the latest advances of MARCH family proteins' emerging roles during viral infections.
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页数：5
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