A revised picture of the E2F transcriptional network and RB function

被引：337
|
作者：
Stevaux, O [1 ]
Dyson, NJ [1 ]
机构：
[1] Massachusetts Gen Hosp, Ctr Canc, Mol Oncol Lab, Charlestown, MA 02129 USA
来源：
CURRENT OPINION IN CELL BIOLOGY | 2002年 / 14卷 / 06期
关键词：
D O I：
10.1016/S0955-0674(02)00388-5
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
New techniques have enhanced our picture of E2F regulation. These studies have shed light on the roles played by individual E2F and retinoblastoma family members and implicate these proteins in processes extending well beyond the G1/S transition. One thorny issue remains: do our current molecular models of E2F and retinoblastoma action explain all of the functions of these proteins in vivo?
引用
收藏
页码：684 / 691
页数：8
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