Mismatch repair: Choreographing accurate strand excision

被引:3
|
作者
Fishel, Richard [1 ,2 ]
机构
[1] Ohio State Univ, Wexner Med Ctr, Dept Canc Biol & Genet, Columbus, OH 43210 USA
[2] James Comprehens Canc Ctr, Columbus, OH 43210 USA
关键词
DNA; SYSTEM;
D O I
10.1016/j.cub.2021.02.001
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
State-of-the-art genetic and cellular studies uniquely implicate the S. cerevisiae Pms1 endonuclease (human PMS2) and ExoI as the major components that produce and/or maintain the strand-specific nicks that precisely direct mismatch repair.
引用
收藏
页码:R293 / R296
页数:4
相关论文
共 50 条
  • [31] In Vitro reconstitution of human mismatch repair and identification of a novel mismatch excision-stimulatory factor
    Li, Guo-Min
    Zhang, Yanbin
    Yuan, Fenghua
    Presnell, Steven
    Tian, Keli
    Gao, Yin
    Wang, Daojing
    Gu, Liya
    [J]. CANCER RESEARCH, 2006, 66 (08)
  • [32] Ribonucleotides Are Signals for Mismatch Repair of Leading-Strand Replication Errors
    Lujan, Scott A.
    Williams, Jessica S.
    Clausen, Anders R.
    Clark, Alan B.
    Kunkel, Thomas A.
    [J]. MOLECULAR CELL, 2013, 50 (03) : 437 - 443
  • [33] DNA mismatch repair-induced double-strand breaks
    Nowosielska, Anetta
    Marinus, M. G.
    [J]. DNA REPAIR, 2008, 7 (01) : 48 - 56
  • [34] Mismatch Repair Balances Leading and Lagging Strand DNA Replication Fidelity
    Lujan, Scott A.
    Williams, Jessica S.
    Pursell, Zachary F.
    Abdulovic-Cui, Amy A.
    Clark, Alan B.
    McElhinny, Stephanie A. Nick
    Kunkel, Thomas A.
    [J]. PLOS GENETICS, 2012, 8 (10):
  • [35] Endonuclease-independent DNA mismatch repair processes on the lagging strand
    Josephs, Eric A.
    Marszalek, Piotr E.
    [J]. DNA REPAIR, 2018, 68 : 41 - 49
  • [36] PCNA function in the activation and strand direction of MutLα endonuclease in mismatch repair
    Pluciennik, Anna
    Dzantiev, Leonid
    Iyer, Ravi R.
    Constantin, Nicoleta
    Kadyrov, Farid A.
    Modrich, Paul
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2010, 107 (37) : 16066 - 16071
  • [37] Base excision repair and double strand break repair cooperate to modulate the formation of unrepaired double strand breaks in mouse brain
    Aris A. Polyzos
    Ana Cheong
    Jung Hyun Yoo
    Lana Blagec
    Sneh M. Toprani
    Zachary D. Nagel
    Cynthia T. McMurray
    [J]. Nature Communications, 15 (1)
  • [38] Double strand breaks in DNA inhibit nucleotide excision repair in vitro
    Calsou, P
    Frit, P
    Salles, B
    [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 1996, 271 (44) : 27601 - 27607
  • [39] DNA double strand break repair and mismatch repair in gastric cancer - Are ATM and BRCA the connection?
    Dattani, M
    Maude, K
    Barker, L
    Gray, S
    Sue-Ling, H
    Dixon, M
    Quirke, P
    Grabsch, H
    [J]. JOURNAL OF PATHOLOGY, 2004, 204 : 31A - 31A
  • [40] Mismatch and base excision repair proficiency in murine embryonic stem cells
    Tichy, Elisia D.
    Liang, Li
    Deng, Li
    Tischfield, Jay
    Schwemberger, Sandy
    Babcock, George
    Stambrook, Peter J.
    [J]. DNA REPAIR, 2011, 10 (04) : 445 - 451