Mismatch repair: Choreographing accurate strand excision

被引：3
|
作者：
Fishel, Richard [1 ,2 ]
机构：
[1] Ohio State Univ, Wexner Med Ctr, Dept Canc Biol & Genet, Columbus, OH 43210 USA
[2] James Comprehens Canc Ctr, Columbus, OH 43210 USA
来源：
CURRENT BIOLOGY | 2021年 / 31卷 / 06期
关键词：
DNA; SYSTEM;
D O I：
10.1016/j.cub.2021.02.001
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
State-of-the-art genetic and cellular studies uniquely implicate the S. cerevisiae Pms1 endonuclease (human PMS2) and ExoI as the major components that produce and/or maintain the strand-specific nicks that precisely direct mismatch repair.
引用
收藏
页码：R293 / R296
页数：4
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