Antiepileptic drugs and epileptic seizures

被引：0

作者：

Karlov, V. A. ^{[1
]}

机构：

[1] Moscow State Med Stomatol Univ, Moscow, Russia

来源：

ZHURNAL NEVROLOGII I PSIKHIATRII IMENI S S KORSAKOVA | 2006年 / 106卷 / 04期

关键词：

antiepileptic drugs; pharmacoresistance; paradoxical reactions;

D O I：

暂无

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Methodological problems of the influence of antiepileptic drugs (AED) on epileptic seizures are characterized. An analysis of 505 patients with diagnosis of pharmacoresistant epilepsy has been conducted. In 187 (37%) patients the causes of treatment resistance were as follows: overtreatment (73 patients; 14,5%), inadequate AED prescription potentially predicted effects - (69 patients; 13,7%), paradoxical reactions to AED (45 patients; 8,9%). Inadequately prescribed were mostly carbamazepine and phenytoin and the drug with paradoxical effect - valproate.

引用

页码：21 / 27

页数：7

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