Direct dehydrative cross-coupling of tautomerizable heterocycles with alkynes via Pd/Cu-catalyzed phosphonium coupling

被引：61
|
作者：
Kang, Fu-An [1 ]
Lanter, James C. [1 ]
Cai, Chaozhong [1 ]
Sui, Zhihua [1 ]
Murray, William V. [1 ]
机构：
[1] Johnson & Johnson Pharmaceut Res & Dev LLC, Spring House, PA 19477 USA
来源：
CHEMICAL COMMUNICATIONS | 2010年 / 46卷 / 08期
关键词：
ARYL BOND FORMATION; C-H; DIRECT ARYLATION; ARYLBORONIC ACIDS; PROTECTING-GROUP; BORONIC ACIDS; ACTIVATION; ARENESULFONATES; ARENES;
D O I：
10.1039/b917777a
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The first chemoselective direct dehydrative cross-coupling of tautomerizable heterocycles with alkynes has been achieved via C-H/C-OH bond activations with direct C(sp(2))-C(sp) bond formation, which is in line with ideal synthesis using readily available materials.
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页码：1347 / 1349
页数：3
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