High concordance of a closed system, near point of care, RT-qPCR breast cancer assay for HER2 (ERBB2) mRNA compared to both IHC/FISH and quantitative immunofluorescence

被引:0
|
作者
Wasserman, B.
Carvajal-Hausdorf, D.
Ho, K.
Wong, W.
Wu, N.
Chu, V. C.
Lai, E. W.
Weidler, J. M.
Bates, M.
Neumenister, V.
Rimm, D. L.
机构
[1] Yale Univ, Sch Med, New Haven, CT USA
[2] Cepheid, Sunnyvale, CA USA
关键词
D O I
10.1158/1538-7445.SABCS16-P1-03-07
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
P1-03-07
引用
收藏
页数:3
相关论文
共 30 条
  • [21] A Five-Plex IHC Assay for Detecting the Status of Hormone Receptor, Her2 and 'Basal-Like' Subtype on FFPE Tissues Demonstrates High Concordance to Single IHC Tests in Invasive Breast Cancer
    Liu, Haiping
    Muralitharan, Sharmini
    LABORATORY INVESTIGATION, 2017, 97 : 56A - 56A
  • [22] Concordance between HER-2 status determined by qPCR in Fine Needle Aspiration Cytology (FNAC) samples compared with IHC and FISH in Core Needle Biopsy (CNB) or surgical specimens in breast cancer patients
    Rodriguez, Claudia
    Suciu, Voichita
    Poterie, Audrey
    Lacroix, Ludovic
    Miran, Isabelle
    Boichard, Amelie
    Delaloge, Suzette
    Deneuve, Jacqueline
    Azoulay, Sandy
    Mathieu, Marie-Christine
    Valent, Alexander
    Michiels, Stefan
    Arnedos, Monica
    Vielh, Philippe
    MOLECULAR ONCOLOGY, 2016, 10 (09) : 1430 - 1436
  • [23] Assessment or Her2 status in breast cancer:: Automated Cellular Imaging System (ACIS™) -: Assisted quantitation of immunohistochemical assay (IHC) improves its correlation with fluorescence in situ hybridization assay (FISH).
    Wang, S
    Saboorian, MH
    Frenkel, E
    Haly, B
    Siddiqui, MT
    Gokaslan, ST
    Ashfaq, R
    MODERN PATHOLOGY, 2001, 14 (01) : 40A - 40A
  • [24] Assessment of Her2 status in breast cancer:: Automated cellular imaging system (ACIS™) -: Assisted quantitation of immunohistochemical assay (IHC) improves its correlation with fluorescence in situ hybridization (FISH).
    Wang, S
    Saboorian, MH
    Frenkel, E
    Haly, B
    Siddiqui, MT
    Gokasian, ST
    Ashfaq, R
    LABORATORY INVESTIGATION, 2001, 81 (01) : 40A - 40A
  • [25] Development and analytical validation of a novel real-time multiplex RT-qPCR assay for the simultaneous quantification of ER, PR, HER-2 and EGFR mRNA expression in circulating tumor cells of breast cancer patients
    Strati, Areti D.
    Lianidou, Evi S.
    CANCER RESEARCH, 2014, 74 (19)
  • [26] Technical validation of an RT-qPCR in vitro diagnostic test system for the determination of breast cancer molecular subtypes by quantification of ERBB2, ESR1, PGR and MKI67 mRNA levels from formalin-fixed paraffin-embedded breast tumor specimens
    Mark Laible
    Kornelia Schlombs
    Katharina Kaiser
    Elke Veltrup
    Stefanie Herlein
    Sotiris Lakis
    Robert Stöhr
    Sebastian Eidt
    Arndt Hartmann
    Ralph M. Wirtz
    Ugur Sahin
    BMC Cancer, 16
  • [27] Technical validation of an RT-qPCR in vitro diagnostic test system for the determination of breast cancer molecular subtypes by quantification of ERBB2, ESR1, PGR and MKI67 mRNA levels from formalin-fixed paraffin-embedded breast tumor specimens
    Laible, Mark
    Schlombs, Kornelia
    Kaiser, Katharina
    Veltrup, Elke
    Herlein, Stefanie
    Lakis, Sotiris
    Stoehr, Robert
    Eidt, Sebastian
    Hartmann, Arndt
    Wirtz, Ralph M.
    Sahin, Ugur
    BMC CANCER, 2016, 16
  • [28] Relapsed Classic E-Cadherin (CDH1) Mutated Invasive Lobular Breast Cancer (ILC) Features IHC/FISH Negative HER2 (ERBB2) Gene Mutations Sensitive to Anti-HER2 Targeted Therapies: A Next Generation Sequencing (NGS) Study
    Ross, J. S.
    Sheehan, C.
    Boguniewicz, A.
    Otto, G.
    Downing, S.
    Curran, J.
    Palmer, G.
    Ali, S.
    Yelensky, R.
    Lipson, D.
    Miller, V.
    Stephens, P.
    MODERN PATHOLOGY, 2013, 26 : 65A - 65A
  • [29] Relapsed Classic E-Cadherin (CDH1) Mutated Invasive Lobular Breast Cancer (ILC) Features IHC/FISH Negative HER2 (ERBB2) Gene Mutations Sensitive to Anti-HER2 Targeted Therapies: A Next Generation Sequencing (NGS) Study
    Ross, J. S.
    Sheehan, C.
    Boguniewicz, A.
    Otto, G.
    Downing, S.
    Curran, J.
    Palmer, G.
    Ali, S.
    Yelensky, R.
    Lipson, D.
    Miller, V.
    Stephens, P.
    LABORATORY INVESTIGATION, 2013, 93 : 65A - 65A
  • [30] A Venezuelan Study of Breast Cancer Estrogen Receptor, Progesterone Receptor and HER2 Receptor Expression by the Standard Method, Immunohistochemistry (IHC), Compared to a New Method, Quantitative Reverse Transcription Polymerase Chain Reaction (RT-PCR).
    Marin, C-E M.
    Ramirez, A. C.
    Baehner, F. L.
    Yoshizawa, C.
    Acosta, M. M.
    CANCER RESEARCH, 2011, 71