High concordance of a closed system, near point of care, RT-qPCR breast cancer assay for HER2 (ERBB2) mRNA compared to both IHC/FISH and quantitative immunofluorescence

被引:0
|
作者
Wasserman, B.
Carvajal-Hausdorf, D.
Ho, K.
Wong, W.
Wu, N.
Chu, V. C.
Lai, E. W.
Weidler, J. M.
Bates, M.
Neumenister, V.
Rimm, D. L.
机构
[1] Yale Univ, Sch Med, New Haven, CT USA
[2] Cepheid, Sunnyvale, CA USA
关键词
D O I
10.1158/1538-7445.SABCS16-P1-03-07
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
P1-03-07
引用
收藏
页数:3
相关论文
共 30 条
  • [1] High concordance of a closed-system, RT-qPCR breast cancer assay for HER2 mRNA, compared to clinically determined immunohistochemistry, fluorescence in situ hybridization, and quantitative immunofluorescence
    Wasserman, Brad E.
    Carvajal-Hausdorf, Daniel E.
    Ho, Kenneth
    Wong, Wendy
    Wu, Natalie
    Chu, Victor C.
    Lai, Edwin W.
    Weidler, Jodi M.
    Bates, Michael
    Neumeister, Veronique
    Rimm, David L.
    LABORATORY INVESTIGATION, 2017, 97 (12) : 1521 - 1526
  • [2] Macrodissection prior to closed system RT-qPCR is not necessary for estrogen receptor and HER2 concordance with IHC/FISH in breast cancer
    Gupta, Swati
    Mani, Navin R.
    Carvajal-Hausdorf, Daniel E.
    Bossuyt, Veerle
    Ho, Kenneth
    Weidler, Jodi
    Wong, Wendy
    Rhees, Brian
    Bates, Michael
    Rimm, David L.
    LABORATORY INVESTIGATION, 2018, 98 (08) : 1076 - 1083
  • [3] Macrodissection prior to closed system RT-qPCR is not necessary for estrogen receptor and HER2 concordance with IHC/FISH in breast cancer
    Gupta, Swati
    Carvajal-Hausdorf, Daniel E.
    Wasserman, Brad E.
    Ho, Kenneth
    Weidler, Jodi
    Wong, Wendy
    Rhees, Brian
    Bates, Michael
    Rimm, David L.
    CANCER RESEARCH, 2018, 78 (04)
  • [4] High concordance of ER, PR, HER2 and Ki67 by central IHC and FISH with mRNA measurements by GeneXper® breast cancer stratifier assay
    Wu, N. C.
    Wong, W.
    Ho, K. E.
    Chu, V. C.
    Rizo, A.
    Davonport, S.
    Kelly, D.
    Makar, R.
    Jassem, J.
    Duchnowska, R.
    Biernat, W.
    Radecka, B.
    Fujita, T.
    Klein, J. L.
    Stonecypher, M.
    Ohta, S.
    Juhl, H.
    Weidler, J. M.
    Bates, M.
    Press, M. F.
    CANCER RESEARCH, 2017, 77
  • [5] The detection of ESR1/PGR/ERBB2 mRNA levels by RT-QPCR: a better approach for subtyping breast cancer and predicting prognosis
    Du, Xin
    Li, Xiao-Qing
    Li, Lin
    Xu, Yuan-Yuan
    Feng, Yu-Mei
    BREAST CANCER RESEARCH AND TREATMENT, 2013, 138 (01) : 59 - 67
  • [6] The detection of ESR1/PGR/ERBB2 mRNA levels by RT-QPCR: a better approach for subtyping breast cancer and predicting prognosis
    Xin Du
    Xiao-Qing Li
    Lin Li
    Yuan-Yuan Xu
    Yu-Mei Feng
    Breast Cancer Research and Treatment, 2013, 138 : 59 - 67
  • [7] Comparison of ER, PR, HER2 and Ki67 expression by MammaTyper® RT-qPCR and immunohistochemistry (IHC) on needle core biopsies of breast cancer
    Shaaban, A.
    Badr, N.
    Zaakouk, M.
    Kearns, D.
    Kong, A.
    EUROPEAN JOURNAL OF CANCER, 2022, 175 : S87 - S88
  • [8] Comparison of central laboratory assessments of ER, PR, HER2, and Ki67 by IHC/FISH and the corresponding mRNAs (ESR1, PGR, ERBB2, and MKi67) by RT-qPCR on an automated, broadly deployed diagnostic platform
    Wu, Natalie C.
    Wong, Wendy
    Ho, Kenneth E.
    Chu, Victor C.
    Rizo, Annaliza
    Davenport, Simon
    Kelly, Devon
    Makar, Rosemary
    Jassem, Jacek
    Duchnowska, Renata
    Biernat, Wojciech
    Radecka, Barbara
    Fujita, Tomoyuki
    Klein, Jonathan L.
    Stonecypher, Mark
    Ohta, Shoichiro
    Juhl, Hartmut
    Weidler, Jodi M.
    Bates, Michael
    Press, Michael F.
    BREAST CANCER RESEARCH AND TREATMENT, 2018, 172 (02) : 327 - 338
  • [9] Comparison of central laboratory assessments of ER, PR, HER2, and Ki67 by IHC/FISH and the corresponding mRNAs (ESR1, PGR, ERBB2, and MKi67) by RT-qPCR on an automated, broadly deployed diagnostic platform
    Natalie C. Wu
    Wendy Wong
    Kenneth E. Ho
    Victor C. Chu
    Annaliza Rizo
    Simon Davenport
    Devon Kelly
    Rosemary Makar
    Jacek Jassem
    Renata Duchnowska
    Wojciech Biernat
    Barbara Radecka
    Tomoyuki Fujita
    Jonathan L. Klein
    Mark Stonecypher
    Shoichiro Ohta
    Hartmut Juhl
    Jodi M. Weidler
    Michael Bates
    Michael F. Press
    Breast Cancer Research and Treatment, 2018, 172 : 327 - 338
  • [10] Testing IHC Equivocal Human Epidermal Growth Factor Receptor 2 (ERBB2/HER2) samples by FISH: Impact of Updated 2013 ASCO/CAP Breast Cancer Guidelines
    Casey, J.
    Bhargava, R.
    Gurda, G. T.
    Surti, U.
    JOURNAL OF MOLECULAR DIAGNOSTICS, 2016, 18 (06): : 1027 - 1027