Reaction of 5-arylfuran-2(3H)-ones with amines

被引：2
|
作者：
Potikha, L. M. [1 ]
Lysakovskii, A. A. [1 ]
Kovtunenko, V. A. [1 ]
Turov, A. V. [1 ]
机构：
[1] Taras Shevchenko Kiev Natl Univ, UA-01033 Kiev, Ukraine
来源：
RUSSIAN JOURNAL OF ORGANIC CHEMISTRY | 2009年 / 45卷 / 12期
关键词：
ACID;
D O I：
10.1134/S1070428009120112
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
5-(4-Chlorophenyl)- and 5-phenylfuran-2(3H)-ones reacted with guanidine carbonate at the methylene group in the unsaturated lactone molecule, leading to the formation of 4-(2-aryl-5-oxo-2,5-dihydrofuran-2-yl)-5-aryltetrahydrofuran-2-ones, while 5-(4-methylphenyl)furan-2(3H)-one under analogous conditions gave rise to N,N'-bis[4-(4-methylphenyl)-4-oxobutanoyl]guanidine. The reactions of 5-arylfuran-2(3H)- ones with thioacetamide afforded 4-aryl-N-{1-[5-aryl-2-oxo-2,3-dihydrofuran-3-ylidene]ethyl}-4-oxobutanamides. The corresponding N-(4-aryl-4-oxobutanoyl)thioureas were obtained by heating 5-arylfuran-2(3H)-ones with thiourea.
引用
收藏
页码：1818 / 1823
页数：6
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