Synthesis of 2,3-dihydrobenzo[1,4]dioxins and -oxazins via a domino Wacker-Heck reaction

被引：0
|
作者：
Tietze, Lutz F. [1 ]
Wilckens, Kristina F. [1 ]
Yilmaz, Sinem [1 ]
Stecker, Florian [1 ]
Zinngrebe, Julia [1 ]
机构：
[1] Univ Gottingen, Inst Organ & Biomol Chem, D-37077 Gottingen, Germany
来源：
HETEROCYCLES | 2006年 / 70卷
关键词：
domio reacton; Wacker reaction; Heck reaction; palladium; heterocycle;
D O I：
暂无
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
An efficient and operationally simple domino Wacker-Heck reaction of allylic phenols and alpha,beta-unsaturated ketones as well as esters in the presence of catalytic amounts of Pd(TFA)(2) and an oxidant for the synthesis of 2,3-dihydrobcnzo[1,4]dioxins and 2,3-dihydrobenzo[1,4]oxazins is described. The necessary substrates are prepared by monoallylation of catechol derivatives and ortho-aminophenol.
引用
收藏
页码：309 / +
页数：12
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