Multipotential Capacity of Human Adipose-derived Mesenchymal Stem Cells

被引：0
|
作者：
Guo, Bao-Feng [1 ]
Zhang, Ling [1 ]
Yin, Wei-Tian [1 ]
Ji, Kun [1 ]
Wei, Zhuang [1 ]
机构：
[1] Jilin Univ, Dept Surg, Prostate Dis Prevent & Treatment Res Ctr, China Japan Union Hosp,Norman Bethune Med Sch, Changchun, Peoples R China
来源：
2010 4TH INTERNATIONAL CONFERENCE ON BIOINFORMATICS AND BIOMEDICAL ENGINEERING (ICBBE 2010) | 2010年
基金：
中国国家自然科学基金;
关键词：
articular cartilage; adipose tissue; stem cell; chondrocyte; TISSUE; REGENERATION;
D O I：
暂无
中图分类号：
R318 [生物医学工程];
学科分类号：
0831 ;
摘要：
Adipose tissue is derived from the embryonic mesenchyme and can be isolated easily. The purpose of this study was to investigate the multipotent ability of adipose-derived mesenchymal stem cells and to investigate the molecular characterization of adipose-derived mesenchymal stem cells during chondrogenic differentiation in vitro. Our results showed that adipose- derived mesenchymal stem cells have the ability to differentiate into adipogenic, osteogenic, and chondrogenic cells with adipogenic, osteogenic, and chondrogenic medium in vitro. The expression of chondrogenic related molecules were detected by RT-PCR analysis during chondrogenic differentiation. These studies demonstrate that human adipose- derived mesenchymal stem cells have the multipotentiality and adipose tissue may represent a novel approach to form tissue engineering cartilage to heal the damage cartilage.
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