Synthesis, characterization and antibacterial activity of some Schiff bases of 2-amino-3-(N-tolyl carboxamido)-4,5,6,7-tetrahydro benzo (b) thiophenes

被引：0
|
作者：
Mohan, S [1 ]
Saravanan, J [1 ]
机构：
[1] MS Ramaiah Coll Pharm, Bangalore 560054, Karnataka, India
来源：
ASIAN JOURNAL OF CHEMISTRY | 2003年 / 15卷 / 01期
关键词：
synthesis; thiophenes; Schiff bases; antibacterial activity;
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
2-Amino-3-(N-tolyl carboxamido)-4,5,6,7-tetrahydro benzo (b) thiophenes (I-III) were synthesized by Gewald reaction. Later, the compounds I-III were treated with ten different substituted arylaldehydes to yield thirty new Schiff bases (I a-j to III a-j). The compounds were characterized by spectral data and were screened for antibacterial activity. Some of these Schiff bases exhibited promising activity.
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页码：67 / 70
页数：4
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