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Synthesis, characterization and antibacterial activity of some Schiff bases of 2-amino-3-(N-tolyl carboxamido)-4,5,6,7-tetrahydro benzo (b) thiophenes
被引:0
|作者:
Mohan, S
[1
]
Saravanan, J
[1
]
机构:
[1] MS Ramaiah Coll Pharm, Bangalore 560054, Karnataka, India
关键词:
synthesis;
thiophenes;
Schiff bases;
antibacterial activity;
D O I:
暂无
中图分类号:
O6 [化学];
学科分类号:
0703 ;
摘要:
2-Amino-3-(N-tolyl carboxamido)-4,5,6,7-tetrahydro benzo (b) thiophenes (I-III) were synthesized by Gewald reaction. Later, the compounds I-III were treated with ten different substituted arylaldehydes to yield thirty new Schiff bases (I a-j to III a-j). The compounds were characterized by spectral data and were screened for antibacterial activity. Some of these Schiff bases exhibited promising activity.
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页码:67 / 70
页数:4
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