Association of hepatitis C virus and HIV infection with subclinical atherosclerosis in the women's interagency HIV study

被引：33
|
作者：
Tien, Phyllis C. [1 ,2 ]
Schneider, Michael F. [3 ]
Cole, Stephen R. [4 ]
Cohen, Mardge H. [5 ,6 ]
Glesby, Marshall J. [7 ]
Lazar, Jason [8 ]
Young, Mary [9 ]
Mack, Wendy [10 ]
Hodis, Howard N. [11 ]
Kaplan, Robert C. [12 ]
机构：
[1] Univ Calif San Francisco, VAMC, Infect Dis Sect, Dept Med, San Francisco, CA 94121 USA
[2] San Francisco VA Med Ctr, San Francisco, CA USA
[3] Johns Hopkins Bloomberg Sch Publ Hlth, Dept Epidemiol, Baltimore, MD USA
[4] Gillings Sch Global Publ Hlth, Dept Epidemiol, Chapel Hill, NC USA
[5] Stroger Hosp, Dept Med, Chicago, IL USA
[6] Rush Univ, Chicago, IL 60612 USA
[7] Weill Cornell Med Coll, Dept Med, New York, NY USA
[8] SUNY Hlth Sci Ctr, Dept Med, Brooklyn, NY 11203 USA
[9] Georgetown Univ, Med Ctr, Dept Med, Washington, DC 20007 USA
[10] Univ So Calif, Dept Prevent Med, Los Angeles, CA 90089 USA
[11] Univ So Calif, Atherosclerosis Res Unit, Los Angeles, CA USA
[12] Albert Einstein Coll Med, Dept Epidemiol & Populat Hlth, Bronx, NY 10467 USA
来源：
AIDS | 2009年 / 23卷 / 13期
关键词：
INTIMA-MEDIA THICKNESS; CORONARY-HEART-DISEASE; CAROTID-ARTERY; RISK-FACTORS; INDIVIDUALS; PROGRESSION;
D O I：
10.1097/QAD.0b013e32832d7aa8
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Whether hepatitis C virus coinfection might accelerate atherosclerosis in HIV-infected individuals is unclear. We examined the relationship of HIV and hepatitis C virus with carotid artery intima media thickness and the presence of carotid plaques in the Women's Interagency HIV Study. Hepatitis C virus infection was not associated with greater carotid artery intima media thickness after adjustment for demographic and traditional cardiovascular risk factors. Further follow-up is needed to clarify whether HIV/hepatitis C virus coinfection may be associated with a greater risk of carotid plaque.
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页码：1781 / 1784
页数：4
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