Poorly differentiated primary pulmonary synovial sarcoma confirmed by detection of the SYT-SSX fusion gene: a case report with a literature review

We present a rare case of a poorly differentiated primary synovial lung sarcoma, which infiltrated the pleura with pleural effusion in a 45-year-old man. Chest CT scan showed a well-defined mass in the inferior right pulmonary lobe. The patient underwent a right middle and lower lobectomy, with lymph node dissection. Findings from imaging and histological and immunohistochemical testing led to a diagnosis of poorly differentiated synovial sarcoma, which was confirmed by genetic testing, which detected the SYT-SSX gene. We also present a brief review of the literature.