Positron Emission Tomography (PET) Imaging of Multiple Myeloma in a Post-Treatment Setting

被引：2
|
作者：
Ferrarazzo, Giulia [1 ,2 ]
Chiola, Silvia [3 ]
Capitanio, Selene [4 ]
Donegani, Maria Isabella [1 ,2 ]
Miceli, Alberto [1 ,2 ]
Raffa, Stefano [1 ,2 ]
Tagliafico, Alberto Stefano [1 ,5 ]
Morbelli, Silvia [1 ,2 ]
Bauckneht, Matteo [1 ,2 ]
机构：
[1] IRCCS Osped Policlin San Martino, I-16132 Genoa, Italy
[2] Univ Genoa, Dept Hlth Sci, Nucl Med Unit, I-16132 Genoa, Italy
[3] Humanitas Clin & Res Ctr IRCCS, Dept Nucl Med, I-20089 Milan, Italy
[4] ASST Grande Osped Metropolitano Niguarda, Dept Adv Diagnost Therapeut Technol, Nucl Med, I-20162 Milan, Italy
[5] Univ Genoa, Dept Hlth Sci, Radiol Unit, I-16132 Genoa, Italy
来源：
DIAGNOSTICS | 2021年 / 11卷 / 02期
关键词：
multiple myeloma; positron emission tomography; magnetic resonance imaging; response assessment; CONTRAST-ENHANCED MRI; WHOLE-BODY MRI; F-18-FDG PET/CT; FDG PET/CT; COMPUTED-TOMOGRAPHY; INTERPRETATION CRITERIA; RESPONSE EVALUATION; FOLLOW-UP; PREDICTION; THERAPY;
D O I：
10.3390/diagnostics11020230
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
2-deoxy-2-[18F]fluoro-D-glucose (FDG) positron emission tomography/computed tomography (FDG PET/CT) has an established clinical value in the diagnosis and initial staging of multiple myeloma (MM). In the last ten years, a vast body of literature has shown that this tool can also be of high relevance for monitoring therapy responses, making it the recommended imaging approach in this field. Starting from the strengths and weaknesses of radiological imaging in MM, the present review aims to analyze FDG PET/CT's current clinical value focusing on therapy response assessment and objective interpretation criteria for therapy monitoring. Given the potential occurrence of patients with MM showing non-FDG-avid bone disease, new opportunities can be provided by non-FDG PET tracers. Accordingly, the potential role of non-FDG PET tracers in this setting has also been discussed.
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页数：18
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