Immobilising giant unilamellar vesicles with zirconium metal-organic framework anchors

被引：0

作者：

Jennings, Christopher S. ^{[1
]}

Rossman, Jeremy S. ^{[2
]}

Hourihan, Braeden A. ^{[1
]}

Marshall, Ross J. ^{[3
]}

Forgan, Ross S. ^{[3
]}

Blight, Barry A. ^{[1
]}

机构：

[1] Univ New Brunswick, Dept Chem, Fredericton, NB E3B 5A3, Canada

[2] Univ Kent, Sch Biosci, Canterbury CT2 7NH, Kent, England

[3] Univ Glasgow, Sch Chem, WestCHEM, Univ Ave, Glasgow G12 8QQ, Lanark, Scotland

来源：

SOFT MATTER | 2021年 / 17卷 / 08期

基金：

加拿大自然科学与工程研究理事会; 英国工程与自然科学研究理事会;

关键词：

Synchrotrons - Lipid bilayers - Metal-Organic Frameworks - Organic polymers;

D O I：

10.1039/d0sm02188a

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

Lipid bilayer vesicles have provided a window into the function and fundamental properties of cells. However, as is the case for most living and soft matter, vesicles do not remain still. This necessitates some microscopy experiments to include a preparatory immobilisation step. Here, we describe a straightforward method to immobilise giant unilamellar vesicles (GUVs) using zirconium-based metal-organic frameworks (MOFs) and demonstrate that GUVs bound in this way will stay in position on a timescale of minutes to hours.

引用

页码：2024 / 2027

页数：4

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