Temozolomide-Resistant Glioma Cells Are Sensitive to Chloroethylating Nitrosourea Compounds in Combination with ATR Inhibitors

被引：0
|
作者：
Jackson, C. [1 ]
Kalathil, A. N. [1 ]
Sundaram, R. K. [2 ]
Bindra, R. S. [1 ]
机构：
[1] Yale Univ, New Haven, CT USA
[2] Yale Univ, Sch Med, New Haven, CT USA
来源：
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS | 2019年 / 105卷 / 01期
关键词：
D O I：
10.1016/j.ijrobp.2019.06.1098
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
3481
引用
收藏
页码：E639 / E639
页数：1
相关论文
共 50 条
  • [31] MGMT-inhibitor in combination with TGF-βRI inhibitor or CDK 4/6 inhibitor increases temozolomide sensitivity in temozolomide-resistant glioblastoma cells
    A. Das
    F. C. Henderson
    M. Alshareef
    G. B. F. Porto
    I. Kanginakudru
    L. K. Infinger
    W. A. Vandergrift
    S. M. Lindhorst
    A. K. Varma
    S. J. Patel
    D. Cachia
    Clinical and Translational Oncology, 2021, 23 : 612 - 619
  • [32] ATR INHIBITORS IN COMBINATION WITH RADIATION AND TEMOZOLOMIDE INCREASE CELL DEATH OF PATIENT-DERIVED GLIOBLASTOMA CELLS
    Lozinski, Mathew
    Bowden, Nikola
    Fay, Michael
    Graves, Moira
    Day, Bryan
    Stringer, Brett
    Tooney, Paul
    NEURO-ONCOLOGY, 2024, 26
  • [33] MGMT-inhibitor in combination with TGF-βRI inhibitor or CDK 4/6 inhibitor increases temozolomide sensitivity in temozolomide-resistant glioblastoma cells
    Das, A.
    Henderson, F. C., Jr.
    Alshareef, M.
    Porto, G. B. F.
    Kanginakudru, I.
    Infinger, L. K.
    Vandergrift, W. A., III
    Lindhorst, S. M.
    Varma, A. K.
    Patel, S. J.
    Cachia, D.
    CLINICAL & TRANSLATIONAL ONCOLOGY, 2021, 23 (03): : 612 - 619
  • [34] Glutathione depletion sensitizes cisplatin- and temozolomide-resistant glioma cells in vitro and in vivo (vol 5, e1505, 2014)
    Rocha, C. R. R.
    Garcia, C. C. M.
    Vieira, D. B.
    Quinet, A.
    de Andrade-Lima, L. C.
    Munford, V.
    Belizario, J. E.
    Menck, C. F. M.
    CELL DEATH & DISEASE, 2015, 6 : e1727 - e1727
  • [35] Fasudil increases temozolomide sensitivity and suppresses temozolomide-resistant glioma growth via inhibiting ROCK2/ABCG2
    Xin Zhang
    Xiuting Liu
    Wei Zhou
    Mengdi Yang
    Yang Ding
    Qing Wang
    Rong Hu
    Cell Death & Disease, 9
  • [36] Fasudil increases temozolomide sensitivity and suppresses temozolomide-resistant glioma growth via inhibiting ROCK2/ABCG2
    Zhang, Xin
    Liu, Xiuting
    Zhou, Wei
    Yang, Mengdi
    Ding, Yang
    Wang, Qing
    Hu, Rong
    CELL DEATH & DISEASE, 2018, 9
  • [37] MicroRNA-21 Inhibition Enhances In Vitro Chemosensitivity of Temozolomide-resistant Glioblastoma Cells
    Wong, Stanley Thian Sze
    Zhang, Xiao-Qin
    Zhuang, James Tin-Fong
    Chan, Hin-Lun
    Li, Chi-Han
    Leung, Gilberto Ka Kit
    ANTICANCER RESEARCH, 2012, 32 (07) : 2835 - 2841
  • [38] Myxoma virotherapy targeting temozolomide-resistant brain tumor initiating cells in vitro and in vivo
    Lun, Xueqing
    Forsyth, Peter A.
    Senger, Donna L.
    Robbins, Stephen
    Kelly, John J. P.
    Weiss, Samuel
    Bell, John
    McFadden, Grant
    CANCER RESEARCH, 2010, 70
  • [39] Olaparib Is a Mitochondrial Complex I Inhibitor That Kills Temozolomide-Resistant Human Glioblastoma Cells
    Zampieri, Luca X.
    Sboarina, Martina
    Cacace, Andrea
    Grasso, Debora
    Thabault, Leopold
    Hamelin, Loic
    Vazeille, Thibaut
    Dumon, Elodie
    Rossignol, Rodrigue
    Frederick, Raphael
    Sonveaux, Etienne
    Lefranc, Florence
    Sonveaux, Pierre
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2021, 22 (21)
  • [40] Temozolomide Sensitizes MGMT-Deficient Tumor Cells to ATR Inhibitors
    Jackson, Christopher B.
    Noorbakhsh, Seth I.
    Sundaram, Ranjini K.
    Kalathil, Aravind N.
    Ganesa, Sachita
    Jia, Lanqi
    Breslin, Hank
    Burgenske, Danielle M.
    Gilad, Oren
    Sarkaria, Jann N.
    Bindra, Ranjit S.
    CANCER RESEARCH, 2019, 79 (17) : 4331 - 4338
12345