Screening of differentially expressed genes in four pancreatic cancer cell lines by cDNA microarray

被引：0
|
作者：
Ohno, K [1 ]
Hata, F [1 ]
Nishimori, H [1 ]
Yasoshima, T [1 ]
Nomura, H [1 ]
Nakajima, F [1 ]
Tanaka, H [1 ]
Kamiguchi, K [1 ]
Sato, N [1 ]
Denno, R [1 ]
Hirata, K [1 ]
机构：
[1] Sapporo Med Univ, Sch Med, Dept Surg 1, Sapporo, Hokkaido, Japan
来源：
XXXIII WORLD CONGRESS OF THE INTERNATIONAL COLLEGE OF SURGEONS - ICS 2002 | 2002年
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中图分类号：
R61 [外科手术学];
学科分类号：
摘要：
To clarify the difference in genes expressed in liver metastasis and peritoneal dissemination, a broad analysis of differential gene: expression analysis between parental cell lines and established metastatic sublines was performed using cDNA microarray. A great number of genes were differentially expressed in metastatic sublines and then compared with each parental cell line. Moreover, 22 genes were identified as potential key genes that could clarify liver metastasis and peritoneal dissemination. Further study will be required; these results provide a new insight into the study of liver metastasis and peritoneal dissemination of pancreatic cancer cells in humans.
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页码：59 / 63
页数：5
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