Nanoparticle temperature estimation in combined ac and dc magnetic fields

被引：78

作者：

Rauwerdink, Adam M. ^{[1
]}

Hansen, Eric W. ^{[1
]}

Weaver, John B. ^{[1
,2
]}

机构：

[1] Dartmouth Coll, Thayer Sch Engn, Hanover, NH 03755 USA

[2] Dartmouth Hitchcock Med Ctr, Dept Radiol, Lebanon, NH 03756 USA

来源：

PHYSICS IN MEDICINE AND BIOLOGY | 2009年 / 54卷 / 19期

关键词：

D O I：

10.1088/0031-9155/54/19/L01

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

The harmonics produced by the nonlinear magnetization of superparamagnetic nanoparticles have been utilized in a number of budding medical devices. Here we expand on an earlier technique for quantitatively measuring nanoparticle temperature in a purely ac field by including the presence of a static field. The ability to quantify nanoparticle temperature by tracking changes in the 4th/2nd harmonic ratio is presented and shown to achieve an accuracy of 0.79 K. The advantage of even harmonics, issues with odd harmonics in the presence of a static field and the potential for future incorporation into an imaging system are discussed.

引用

页码：L51 / L55

页数：5

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