No association between 5-HTTLPR and harm avoidance in Korean college students

被引：9

作者：

Joo, Yeon Ho

Oh, Heung Bum

Kim, Byungsu

Jung, Suk Hoon

Chung, Jun Kyu

Hong, Jin Pyo

Kim, Chang Yoon

机构：

[1] Univ Ulsan, Coll Med, Asan Med Ctr, Dept Psychiat, Seoul 138736, South Korea

[2] Univ Ulsan, Coll Med, Asan Med Ctr, Dept Lab Med, Seoul 138736, South Korea

来源：

JOURNAL OF KOREAN MEDICAL SCIENCE | 2007年 / 22卷 / 01期

关键词：

anxiety-related personality trait; 5-HTTLPR; temperament and character inventory; harm avoidance; Korea; SLC6A4; protein; human; polymorphism; gentic;

D O I：

10.3346/jkms.2007.22.1.138

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

There have been numerous studies on the association between 5-HTTLPR (polymorphisms in the promoter region of the serotonin transporter gene) and anxiety-related personality traits, with conflicting results. In this study, we administered Korean version of the Temperament and Character Inventory (K-TCI) to a sample of 158 Korean college students and genotyped for the 5-HTTLPR in order to compare the TCI dimensional scores including harm avoidance according to the 5-HTTLPR genotype and sex. We could not find the association between 5-HTTLPR and harm avoidance and other TCI measures. Considering known allele frequencies differences of 5-HTTLPR among different ethnic groups, further cross-cultural studies with a larger sample would be needed.

引用

页码：138 / 141

页数：4

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