Two New Metabolites, Epoxydine A and B, from Phoma sp.

被引:21
|
作者
Qin, Song [1 ]
Hussain, Hidayat [1 ]
Schulz, Barbara [2 ]
Draeger, Siegfried [2 ]
Krohn, Karsten [1 ]
机构
[1] Univ Gesamthsch Paderborn, Dept Chem, D-33098 Paderborn, Germany
[2] Tech Univ Carolo Wilhelmina Braunschweig, Inst Mikrobiol, D-31806 Braunschweig, Germany
关键词
ACTIVE SECONDARY METABOLITES; ENDOPHYTIC FUNGI; NATURAL-PRODUCTS; MICROORGANISMS;
D O I
10.1002/hlca.200900199
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The new compounds, epoxydines A and B (1 and 2, resp.). along with the known and related metabolites, 3-6, were isolated from the fungal endophyte Phoma sp. The structures of the new compounds were elucidated by detailed spectroscopic analysis, and the relative configuration of I was confirmed by ROESY experiments. Preliminary studies indicated that compounds 2-5 possess good antibacterial, antifungal, and algicidal properties. Similarly, compound 1 showed antifungal and algicidal, and compound 6 antibacterial and algicidal properties.
引用
收藏
页码:169 / 174
页数:6
相关论文
共 50 条
  • [31] Antimicrobial chemical constituents from endophytic fungus Phoma sp.
    Hussain, Hidayat
    Kock, Ines
    Al-Harrasi, Ahmed
    Al-Rawahi, Ahmed
    Abbas, Ghulam
    Green, Ivan R.
    Shah, Afzal
    Badshah, Amin
    Saleem, Muhammad
    Draeger, Siegfried
    Schulz, Barbara
    Krohn, Karsten
    ASIAN PACIFIC JOURNAL OF TROPICAL MEDICINE, 2014, 7 (09) : 699 - 702
  • [32] Antimicrobial chemical constituents from endophytic fungus Phoma sp.
    Hidayat Hussain
    Ines Kock
    Ahmed Al-Harrasi
    Ahmed Al-Rawahi
    Ghulam Abbas
    Ivan R.Green
    Afzal Shah
    Amin Badshah
    Muhammad Saleem
    Siegfried Draeger
    Barbara Schulz
    Karsten Krohn
    Asian Pacific Journal of Tropical Medicine, 2014, (09) : 699 - 702
  • [33] Bioactive secondary metabolites from an endophytic fungus Phoma sp. PF2 derived from Artemisia princeps Pamp
    Kim, Jung Wha
    Choi, Hyun Gyu
    Song, Ji Hoon
    Kang, Ki Sung
    Shim, Sang Hee
    JOURNAL OF ANTIBIOTICS, 2019, 72 (03): : 174 - 177
  • [34] Secondary Metabolites of Two Desert Endophytic Fungi Neocamarosporum sp. and Alternaria sp.
    Pan, Hua-Yang
    Liu, Hua-Guang
    Liu, Hui-Ying
    Liu, Yu
    Yan, Shuang-Mei
    Zhao, Xiao-Long
    Luo, Du-Qiang
    CHEMISTRY OF NATURAL COMPOUNDS, 2024, 60 (06) : 1021 - 1028
  • [35] Secondary Metabolites from Annulohypoxylon sp. and Structural Revision of Emericellins A and B
    Gan, Dong
    Wang, Cheng-Yao
    Li, Chen-Zhe
    Zhu, Li
    Zhang, Xiao-Ran
    Ding, Hao
    Cai, Le
    Ding, ZhongTao
    JOURNAL OF NATURAL PRODUCTS, 2022, 85 (04): : 828 - 837
  • [36] A New Diphenyl Derivative from Endogenous Phoma sp. Associated with the Edible Mushroom Boletus edulis
    Yang, Shuang
    Shi, Wen-Zhi
    Long, Xing
    Li, Shi-Yu
    Sun, Li-Jingfei
    Ceng, Rong-Huang
    Su, Shuang
    Yang, Xue-Qiong
    Yang, Ya-Bin
    Ding, Zhong-Tao
    CHEMISTRY OF NATURAL COMPOUNDS, 2022, 58 (02) : 261 - 263
  • [37] A New Diphenyl Derivative from Endogenous Phoma sp. Associated with the Edible Mushroom Boletus edulis
    Shuang Yang
    Wen-Zhi Shi
    Xing Long
    Shi-Yu Li
    Li-Jingfei Sun
    Rong-Huang Ceng
    Shuang Su
    Xue-Qiong Yang
    Ya-Bin Yang
    Zhong-Tao Ding
    Chemistry of Natural Compounds, 2022, 58 : 261 - 263
  • [38] Metabolites from the Fungus Phoma sp 7210, Associated with Aizoon canariense
    Dai, Jingqiu
    Hussain, Hidayat
    Draeger, Siegfried
    Schulz, Barbara
    Kurtan, Tibor
    Pescitelli, Gennaro
    Floerke, Ulrich
    Krohn, Karsten
    NATURAL PRODUCT COMMUNICATIONS, 2010, 5 (08) : 1175 - 1180
  • [39] Two new secondary metabolites from the mangrove endophytic fungus Pleosporales sp. SK7
    Wen, Shitong
    Fan, Weilong
    Guo, Huixian
    Huang, Cuiying
    Yan, Zhangyuan
    Long, Yuhua
    NATURAL PRODUCT RESEARCH, 2020, 34 (20) : 2919 - 2925
  • [40] Two New Imidazolone-Containing Alkaloids and Further Metabolites from the Ascomycete Fungus Tricladium sp.
    Zou, Xianwei
    Liu, Shuchun
    Zheng, Zhihui
    Zhang, Hua
    Chen, Xulin
    Liu, Xingzhong
    Li, Erwei
    CHEMISTRY & BIODIVERSITY, 2011, 8 (10) : 1914 - 1920