Fluorinated and hemifluorinated surfactants derived from maltose: Synthesis and application to handling membrane proteins in aqueous solution

被引：22
|
作者：
Polidori, Ange
Presset, Marc
Lebaupain, Florence
Ameduri, Bruno
Popot, Jean-Luc
Breyton, Cecile
Pucci, Bernard
机构：
[1] Univ Avignon & Pays Vaucluse, Lab Chim Bioorgan & Syst Mol Vectoriels, F-84000 Avignon, France
[2] CNRS, UMR 7099, Lab Physicochim Mol Membranes Biol, F-75005 Paris, France
[3] Univ Paris 07, CNRS, Inst Biol Physicochim, FRC 550, F-75005 Paris, France
[4] ENSCM, Lab Chim Macromol, F-34296 Montpellier 5, France
来源：
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 2006年 / 16卷 / 22期
关键词：
fluorinated surfactants; maltoside; membrane proteins; solubilization; aggregates;
D O I：
10.1016/j.bmcl.2006.08.070
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Two novel fluorinated surfactants have been obtained by grafting by radical reaction either a fluorocarbon or an ethyl end-capped fluorocarbon chain onto the double bond of beta-D-allyl maltose. The two compounds thus obtained form polydisperse aggregates in water. They can keep membrane proteins water-soluble, but the protein/surfactant complexes are polydisperse, which affects neither the native state nor the stability of the proteins. (c) 2006 Elsevier Ltd. All rights reserved.
引用
收藏
页码：5827 / 5831
页数：5
相关论文
共 50 条
  • [1] Hemifluorinated surfactants: a non-dissociating environment for handling membrane proteins in aqueous solutions?
    Breyton, C
    Chabaud, E
    Chaudier, Y
    Pucci, B
    Popot, JL
    FEBS LETTERS, 2004, 564 (03) : 312 - 318
  • [2] Stabilization of integral membrane proteins in aqueous solution using fluorinated surfactants
    Chabaud, E
    Barthélémy, P
    Mora, N
    Popot, JL
    Pucci, B
    BIOCHIMIE, 1998, 80 (5-6) : 515 - 530
  • [3] Fluorinated and hemifluorinated surfactants as alternatives to detergents for membrane protein cell-free synthesis
    Park, Kyu-Ho
    Berrier, Catherine
    Lebaupain, Florence
    Pucci, Bernard
    Popot, Jean-Luc
    Ghazi, Alexandre
    Zito, Francesca
    BIOCHEMICAL JOURNAL, 2007, 403 : 183 - 187
  • [4] Chaperoning of insertion of membrane proteins into lipid bilayers by hemifluorinated surfactants: Application to diphtheria toxin
    Palchevskyy, SS
    Posokhov, YO
    Olivier, B
    Popot, JL
    Pucci, B
    Ladokhin, AS
    BIOCHEMISTRY, 2006, 45 (08) : 2629 - 2635
  • [5] Hybrid Fluorinated and Hydrogenated Double-Chain Surfactants for Handling Membrane Proteins
    Legrand, Frederic
    Breyton, Cecile
    Guillet, Pierre
    Ebel, Christine
    Durand, Gregory
    JOURNAL OF ORGANIC CHEMISTRY, 2016, 81 (02): : 681 - 688
  • [6] A diglucosylated fluorinated surfactant to handle integral membrane proteins in aqueous solution
    Abla, Maher
    Durand, Gregory
    Breyton, Cecile
    Raynal, Simon
    Ebel, Christine
    Pucci, Bernard
    JOURNAL OF FLUORINE CHEMISTRY, 2012, 134 : 63 - 71
  • [7] Amphipols, Nanodiscs, and Fluorinated Surfactants: Three Nonconventional Approaches to Studying Membrane Proteins in Aqueous Solutions
    Popot, Jean-Luc
    ANNUAL REVIEW OF BIOCHEMISTRY, VOL 79, 2010, 79 : 737 - 775
  • [8] Synthesis and combined properties of novel fluorinated cationic surfactants derived from hexafluoropropylene dimer
    Chao Lin
    Renming Pan
    Ping Xing
    Biao Jiang
    ChineseChemicalLetters, 2018, 29 (11) : 1613 - 1616
  • [9] Neutral polymeric Surfactants derived from dextran: A study of their aqueous solution behavior
    Rotureau, E
    Chassenieux, C
    Dellacherie, E
    Durand, A
    MACROMOLECULAR CHEMISTRY AND PHYSICS, 2005, 206 (20) : 2038 - 2046
  • [10] Synthesis and combined properties of novel fluorinated cationic surfactants derived from hexafluoropropylene dimer
    Lin, Chao
    Pan, Renming
    Xing, Ping
    Jiang, Biao
    CHINESE CHEMICAL LETTERS, 2018, 29 (11) : 1613 - 1616
12345