Paraoxonase and other coronary risk factors in a community-based cohort

被引:9
|
作者
Cohen, J
Jenkins, AJ
Karschimkus, C
Qing, S
Lee, CT
O'Dea, K
Best, JD
Rowley, KG
机构
[1] Univ Melbourne, Dept Med, Fitzroy, Vic 3065, Australia
[2] Univ N Carolina, Sch Med, Chapel Hill, NC USA
[3] Monash Univ, Dept Biochem & Mol Biol, Clayton, Vic 3168, Australia
[4] Menzies Sch Hlth Res, Casuarina, NT, Australia
关键词
D O I
10.1179/135100002125000848
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Oxidative damage to circulating lipids and vascular tissues contributes to the initiation and progression of atherosclerosis. High density lipoprotein provides protection from atherosclerosis and the enzyme paraoxonase may contribute to this effect. The aim of the present study was to examine the trends in paraoxonase activity during the course of a community-directed life-style intervention, and relationships of paraoxonase activity to other coronary heart disease risk factors, in a cohort of Australian Aboriginal people.
引用
收藏
页码:304 / 307
页数:4
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