A Modeling Study of Glutamate Release of NMDA Receptors

被引:0
|
作者
Blackwell, Justin [1 ]
Su, Jianzhong [1 ]
Kavalali, Ege [1 ]
机构
[1] Univ Texas Arlington, Dept Math, Arlington, TX 76019 USA
关键词
Synapse modeling; Neurotransmission; Independent signaling; NMDA receptors; Diffusion equation; Chemical synapses; CENTRAL SYNAPSE; POOL;
D O I
10.1007/978-90-481-9695-1_47
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
In this chapter we will use a mathematical model to simulate spontaneous and evoked neurotransmission to determine how receptor location on presynaptic density can activate distinct sets of NMDA receptors and signal independently to the postsynaptic side. We will also examine how the release rate of the neurotransmitter Glutamate will affect post-synaptic currents by varying the fusion pore size at the presynaptic side.
引用
收藏
页码:301 / 305
页数:5
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