The mechanism of cancer cell death by PARP inhibitors goes beyond DNA damage alone

被引：6
|
作者：
Maccio, Antonio [1 ]
Madeddu, Clelia [2 ]
机构：
[1] Azienda Osped Brotzu, Dept Gynecol Oncol, Via Jenner, I-09120 Cagliari, Italy
[2] Univ Cagliari, Dept Med Sci & Publ Hlth, Cagliari, Italy
来源：
INTERNATIONAL JOURNAL OF CANCER | 2019年 / 145卷 / 09期
关键词：
POLYMERASE; OLAPARIB;
D O I：
10.1002/ijc.32392
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
引用
收藏
页码：2594 / 2596
页数：3
相关论文
共 50 条
  • [41] Autophagy suppression enhances DNA damage and cell death upon treatment with PARP inhibitor Niraparib in laryngeal squamous cell carcinoma
    Yunxiang Ji
    Qian Wang
    Qian Zhao
    Shuwei Zhao
    Li Li
    Guangbin Sun
    Li Ye
    Applied Microbiology and Biotechnology, 2019, 103 : 9557 - 9568
  • [42] JQ1 induces DNA damage, inhibits expression of DNA repair proteins, and synergizes with PARP inhibitors in pancreatic cancer cells
    Miller, Aubrey Lynn
    Gamblin, Tracy
    Council, Leona
    van Waardenburg, Robert
    Yang, Eddy
    Bradner, James
    Yoon, Karina
    CANCER RESEARCH, 2017, 77
  • [43] Beyond DNA repairs additional functions of PARP-1 in cancer
    Weaver, Alice N.
    Yang, Eddy S.
    FRONTIERS IN ONCOLOGY, 2013, 3
  • [44] Donafenib inhibits PARP1 expression and induces DNA damage, in combination with PARP1 inhibitors promotes apoptosis in liver cancer cells
    Jiang, Jiuliang
    Yang, Pingping
    Xu, Xinyu
    Yuan, Huixiong
    Zhu, Haitao
    ANTI-CANCER DRUGS, 2024, 35 (09) : 789 - 805
  • [45] Calcitriol-induced DNA damage: Toward a molecular mechanism of selective cell death
    Hasan, S. Saif
    Rizvi, Asim
    Naseem, Imrana
    IUBMB LIFE, 2013, 65 (09) : 787 - 792
  • [46] Cell cycle and cell death after DNA damage
    Kastan, MB
    Morgan, SE
    Siliciano, J
    Kirsch, D
    Dennis, P
    Canman, CE
    FASEB JOURNAL, 1997, 11 (09): : A879 - A879
  • [47] The comparative effectiveness of PARP1 inhibitors alone or in combination against sporadic cancer
    De Soto, Joseph
    FASEB JOURNAL, 2011, 25
  • [48] PARP inhibitors and the treatment of breast cancer: beyond BRCA1/2?
    Frizzell, Kristine M.
    Kraus, W. Lee
    BREAST CANCER RESEARCH, 2009, 11 (06):
  • [49] PARP Inhibitors for Breast Cancer: Germline BRCA1/2 and Beyond
    Menezes, Maria Clara Saad
    Raheem, Farah
    Mina, Lida
    Ernst, Brenda
    Batalini, Felipe
    CANCERS, 2022, 14 (17)
  • [50] PARP inhibitors and the treatment of breast cancer: beyond BRCA1/2?
    Kristine M Frizzell
    W Lee Kraus
    Breast Cancer Research, 11
12345