Photonic crystal microring resonator for labelfree biosensing

被引:94
|
作者
Lo, Stanley M. [1 ]
Hu, Shuren [2 ]
Gaur, Girija [1 ]
Kostoulas, Yiorgos [1 ]
Weiss, Sharon M. [1 ,2 ]
Fauchet, Philippe M. [1 ]
机构
[1] Vanderbilt Univ, Dept Elect Engn & Comp Sci, 221 Kirkland Hall, Nashville, TN 37235 USA
[2] Vanderbilt Univ, Dept Phys & Astron, Nashville, TN 37235 USA
来源
OPTICS EXPRESS | 2017年 / 25卷 / 06期
基金
美国国家科学基金会;
关键词
RING-RESONATOR; SLOW-LIGHT; WAVE-GUIDES; SENSITIVITY; DISPERSION; SENSOR; AIR;
D O I
10.1364/OE.25.007046
中图分类号
O43 [光学];
学科分类号
070207 ; 0803 ;
摘要
A label-free optical biosensor based on a one-dimensional photonic crystal microring resonator with enhanced light-matter interaction is demonstrated. More than a 2-fold improvement in volumetric and surface sensing sensitivity is achieved compared to conventional microring sensors. The experimental bulk detection sensitivity is similar to 248nm/RIU and label-free detection of DNA and proteins is reported at the nanomolar scale. With a minimum feature size greater than 100nm, the photonic crystal microring resonator biosensor can be fabricated with the same standard lithographic techniques used to mass fabricate conventional microring resonators. (C) 2017 Optical Society of America
引用
收藏
页码:7046 / 7054
页数:9
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