Oral Cancer Prevention Advances with a Translational Trial of Green Tea

被引：8
|
作者：
Shin, Dong M. [1 ]
机构：
[1] Emory Univ, Winship Canc Inst, Dept Hematol & Med Oncol, Atlanta, GA 30322 USA
来源：
CANCER PREVENTION RESEARCH | 2009年 / 2卷 / 11期
关键词：
SQUAMOUS-CELL CARCINOMA; GROWTH-FACTOR RECEPTOR; LOW-DOSE ISOTRETINOIN; 2ND PRIMARY TUMORS; (-)-EPIGALLOCATECHIN GALLATE; EPIGALLOCATECHIN GALLATE; 13-CIS-RETINOIC ACID; BETA-CAROTENE; STAGE-I; APOPTOSIS;
D O I：
10.1158/1940-6207.CAPR-09-0207
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
This perspective on Tsao et al. (beginning on p. 931 in this issue of the journal) discusses green tea extract, which was shown for the first time to have dose-dependent effects in a clinical chemopreventive setting (oral premalignant lesions). This translational trial provides important data on angiogenesis and other biomarkers on which to base future clinical research, which should include trials of green tea extract or polyphenols combined with other natural or synthetic compounds to enhance chemopreventive effects.
引用
收藏
页码：919 / 921
页数：3
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