Regioselective alkylation of lithium dienediolates of α,β-unsaturated carboxylic acids

被引：0
|
作者：
Brun, EM [1 ]
Gil, S [1 ]
Mestres, R [1 ]
Parra, M [1 ]
机构：
[1] Univ Valencia, Dept Quim Organ, Valencia, Spain
来源：
SYNTHESIS-STUTTGART | 2000年 / 08期
关键词：
lithium enolates; alkylation; alkyl sulfonates; carboxylic acids; diastereoselectivity;
D O I：
暂无
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Lithium carboxylic acids dienediolates are regioselectively alkylated at the a-carbon by reaction with tosylates derived from both primary and secondary alcohols. Both regio- and diastereoselectivity are improved when compared with those obtained in the corresponding alkylation with alkyl halides.
引用
收藏
页码：1160 / 1165
页数：6
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