A Numerical Simulation of Tumor Angiogenesis

被引：1
|
作者：
Liu Shenquan [1 ]
Meng Xiangxiang [1 ]
Zhang Tongbin [2 ]
机构：
[1] South China Univ Technol, Sch Math Sci, Guangzhou 510640, Peoples R China
[2] Henan Univ Technol, Sch Sci, Zhengzhou 450000, Peoples R China
来源：
ICIC 2009: SECOND INTERNATIONAL CONFERENCE ON INFORMATION AND COMPUTING SCIENCE, VOL 3, PROCEEDINGS: APPLIED MATHEMATICS, SYSTEM MODELLING AND CONTROL | 2009年
关键词：
Tumor Angiogenesis; VEGF; Ang-1; Ang-2; Overture; ENDOTHELIAL GROWTH-FACTOR;
D O I：
10.1109/ICIC.2009.208
中图分类号：
TP [自动化技术、计算机技术];
学科分类号：
0812 ;
摘要：
A mathematical model of tumor angiogenesis, regulated by vascular endothelial growth factor (VEGF) and angiopoietins (Ang-1, Ang-2), is presented. The Overture numerical simulation of this model is developed, and the result analysis shows the characteristics of the density changing of endothelial cells, vascular endothelial growth factor and angiopoietins in the extra-cellular matrix in tumor angiogenesis. There is a discussion of the simulation results of the model under four different situations, which shows the different roles of VEGF, Ang-1, Ang-2 and their relationship in tumor angiogenesis.
引用
收藏
页码：11 / +
页数：2
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