Opportunities for microfluidic technologies in synthetic biology

被引:55
|
作者
Gulati, Shelly [1 ,2 ]
Rouilly, Vincent [3 ]
Niu, Xize [1 ,2 ]
Chappell, James [3 ]
Kitney, Richard I. [4 ]
Edel, Joshua B. [1 ,2 ]
Freemont, Paul S. [3 ]
deMello, Andrew J. [1 ]
机构
[1] Univ London Imperial Coll Sci Technol & Med, Dept Chem, London SW7 2AZ, England
[2] Univ London Imperial Coll Sci Technol & Med, Inst Biomed Engn, London SW7 2AZ, England
[3] Univ London Imperial Coll Sci Technol & Med, Div Mol Biosci, London SW7 2AZ, England
[4] Univ London Imperial Coll Sci Technol & Med, Dept Bioengn, London SW7 2AZ, England
基金
英国工程与自然科学研究理事会;
关键词
microfluidic; technologies; engineering principles; POLYMERASE-CHAIN-REACTION; FREE PROTEIN EXPRESSION; MULTIPHASE MICROFLUIDICS; CHEMICAL AMPLIFICATION; DROPLET FORMATION; SINGLE CELLS; FLOW; DNA; SYSTEMS; PHYSICS;
D O I
10.1098/rsif.2009.0083.focus
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
We introduce microfluidics technologies as a key foundational technology for synthetic biology experimentation. Recent advances in the field of microfluidics are reviewed and the potential of such a technological platform to support the rapid development of synthetic biology solutions is discussed.
引用
收藏
页码:S493 / S506
页数:14
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