ANTITUMOR ACTIVITY OF A NOVEL FGFR INHIBITOR IN INTRAHEPATIC CHOLANGIOCARCINOMA

被引：0

作者：

Raggi, Chiara ^{[1
]}

Fiaccadori, Karim ^{[2
]}

Pastore, Mirella ^{[1
]}

Correnti, Margherita ^{[2
]}

Piombanti, Benedetta ^{[1
]}

Forti, Elisa ^{[2
]}

Navari, Nadia ^{[1
]}

Abbadessa, Giovanni ^{[3
]}

Hall, Terence ^{[3
]}

Destro, Annarita ^{[2
]}

Di Tommaso, Luca ^{[4
]}

Roncalli, Massimo ^{[5
]}

Meng, Fanyin ^{[6
,7
]}

Glaser, Shannon S. ^{[8
]}

Rovida, Elisabetta ^{[1
]}

Peraldo-Neia, Caterina ^{[9
]}

Olaizola, Paula ^{[10
]}

Banales, Jesus M. ^{[10
]}

Gerussi, Alessio ^{[11
,12
]}

Elvevi, Alessandra ^{[11
,12
]}

Busset, Michele Droz Dit ^{[13
]}

Bhoori, Sherrie ^{[14
]}

Mazzaferro, Vincenzo ^{[15
]}

Alpini, Gianfranco ^{[16
,17
,18
]}

Marra, Fabio ^{[19
]}

Invernizzi, Pietro ^{[20
]}

机构：

[1] Univ Florence, Florence, Italy

[2] Humanitas Clin & Res Ctr, Rozzano, Italy

[3] Arqule Inc, Woburn, MA USA

[4] Humanitas Res Inst, Rozzano, MI, Italy

[5] Humanitas Res Hosp, Pathol Unit, Rozzano, MI, Italy

[6] Richard L Roudebush VA Med Ctr, Div Gastroenterol & Hepatol, Dept Med, Indianapolis, IN USA

[7] Indiana Univ, Bloomington, IN 47405 USA

[8] Texas A&m Hlth Sci Ctr, Bryan, TX USA

[9] Fdn Edo & Elvo Tempia, Canc Genom Lab 8, Biella, Italy

[10] Univ Basque Country UPV EHU, Dept Liver & Gastrointestinal Dis, Biodonostia Res Inst, Donostia Univ Hosp,Ciberehd,Ikerbasque, Leioa, Spain

[11] Univ Milano Bicocca, Div Gastroenterol, San Gerardo Hosp, Dept Med & Surg, Monza, Italy

[12] Univ Milano Bicocca, Ctr Autoimmune Liver Dis, San Gerardo Hosp, Dept Med & Surg, Monza, Italy

[13] Ist Nazl Tumori Irccs Fdn, Hpb Surg & Liver Transplantat, Milan, Italy

[14] Ist Nazl Tumori Irccs Fdn, Gastroenterol & Liver Transplant Hepatol, Milan, Italy

[15] Natl Tumor Inst, Milan, Italy

[16] Richard L Roudebush VA Med Ctr, Indianapolis, IN USA

[17] Indiana Univ, Gastroenterol, Med, Bloomington, IN 47405 USA

[18] Richard L Roudebush Vet Adm Med Ctr, Indianapolis, IN USA

[19] Univ Florence, Dipartimento Med Sperimentale & Clin, Florence, Italy

[20] Univ Milano Bicocca, Dept Med & Surg, Monza, Italy

来源：

HEPATOLOGY | 2019年 / 70卷

关键词：

D O I：

暂无

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

355

引用

页码：226A / 227A

页数：2

共 50 条

[31] FGFR2 fusions assessed by NGS, FISH, and immunohistochemistry in intrahepatic cholangiocarcinoma
Cao, Zi
Yang, Yichen
Liu, Shasha
Sun, Lin
Liu, Yanxue
Luo, Ye
Wang, Jian
Sun, Yan
JOURNAL OF GASTROENTEROLOGY, 2025, 60 (02) : 235 - 246
[32] FGFR2 fusion and/or rearrangement profiling in Chinese patients with intrahepatic cholangiocarcinoma
Huang, X-W.
Shi, G-M.
Zhang, T.
Bao, L-Q.
Wen, T-F.
Zhang, B.
Peng, T.
Zhao, H.
Kuang, M.
Wang, W-L.
Ran, J-H.
Liu, Y-B.
Gong, W.
Mou, H-B.
Luo, Y.
Wang, Y.
Sun, H.
Fan, J.
Liu, L-X.
Dai, M.
ANNALS OF ONCOLOGY, 2021, 32 : S379 - S379
[33] Detection of FGFR fusions in intrahepatic cholangiocarcinoma using targeted RNA sequencing.
Farooq, Maria
Markus, Havell
McDonald, Bradon
Egan, Jan B.
Contente-Cuomo, Tania
Odenheimer, Ahuva
Fernandez-Zapico, Martin
Borad, Mitesh J.
Murtaza, Muhammed
JOURNAL OF CLINICAL ONCOLOGY, 2021, 39 (15)
[34] Knockdown of FGFR3 inhibits the proliferation, migration and invasion of intrahepatic cholangiocarcinoma
Chen, Yi-hui
Yang, Shao-hua
Liu, Li-xin
Hu, Sheng
Wang, Xue-jun
Liao, Zhou-jun
Huan, Yun-feng
He, Kai
Zhang, Xiao-wen
DIGESTIVE AND LIVER DISEASE, 2023, 55 (03) : 400 - 406
[35] Therapeutic targeting of extracellular FGFR2 activating deletions in intrahepatic cholangiocarcinoma
Cleary, James M.
Raghavan, Srivatsan
Li, Yvonne Y.
Spurr, Liam
Wu, Qibiao
Shi, Lei
Brais, Lauren K.
Odhiambo, Zunelly
Goyal, Lipika
Patel, Anuj K.
Shinagare, Atul B.
Clancy, Thomas E.
Shapiro, Geoffrey
Cerami, Ethan
Sellers, William R.
Hahn, William C.
Cherniack, Andrew D.
Bardeesy, Nabeel
Meyerson, Matthew
Wolpin, Brian M.
JOURNAL OF CLINICAL ONCOLOGY, 2020, 38 (04)
[36] Activated FGFR2 signalling as a biomarker for selection of intrahepatic cholangiocarcinoma patients candidate to FGFR targeted therapies
Brandi, Giovanni
Relli, Valeria
Deserti, Marzia
Palloni, Andrea
Indio, Valentina
Astolfi, Annalisa
Serravalle, Salvatore
Mattiaccio, Alessandro
Vasuri, Francesco
Malvi, Deborah
Deiana, Chiara
Pantaleo, Maria Abbondanza
Cescon, Matteo
Rizzo, Alessandro
Katoh, Masaru
Tavolari, Simona
SCIENTIFIC REPORTS, 2024, 14 (01)
[37] Activated FGFR2 signalling as a biomarker for selection of intrahepatic cholangiocarcinoma patients candidate to FGFR targeted therapies
Giovanni Brandi
Valeria Relli
Marzia Deserti
Andrea Palloni
Valentina Indio
Annalisa Astolfi
Salvatore Serravalle
Alessandro Mattiaccio
Francesco Vasuri
Deborah Malvi
Chiara Deiana
Maria Abbondanza Pantaleo
Matteo Cescon
Alessandro Rizzo
Masaru Katoh
Simona Tavolari
Scientific Reports, 14
[38] Integrated Genomic Characterization Reveals Novel, Therapeutically Relevant Drug Targets in FGFR and EGFR Pathways in Sporadic Intrahepatic Cholangiocarcinoma
Borad, Mitesh J.
Champion, Mia D.
Egan, Jan B.
Liang, Winnie S.
Fonseca, Rafael
Bryce, Alan H.
McCullough, Ann E.
Barrett, Michael T.
Hunt, Katherine
Patel, Maitray D.
Young, Scott W.
Collins, Joseph M.
Silva, Alvin C.
Condjella, Rachel M.
Block, Matthew
McWilliams, Robert R.
Lazaridis, Konstantinos N.
Klee, Eric W.
Bible, Keith C.
Harris, Pamela
Oliver, Gavin R.
Bhavsar, Jaysheel D.
Nair, Asha A.
Middha, Sumit
Asmann, Yan
Kocher, Jean-Pierre
Schahl, Kimberly
Kipp, Benjamin R.
Fritcher, Emily G. Barr
Baker, Angela
Aldrich, Jessica
Kurdoglu, Ahmet
Izatt, Tyler
Christoforides, Alexis
Cherni, Irene
Nasser, Sara
Reiman, Rebecca
Phillips, Lori
McDonald, Jackie
Adkins, Jonathan
Mastrian, Stephen D.
Placek, Pamela
Watanabe, Aprill T.
LoBello, Janine
Han, Haiyong
Von Hoff, Daniel
Craig, David W.
Stewart, A. Keith
Carpten, John D.
PLOS GENETICS, 2014, 10 (02):
[39] FGFR inhibitor resistance in cholangiocarcinoma: current understanding and future directions
Neureiter, Daniel
Ellinghaus, Peter
Ocker, Matthias
EXPERT OPINION ON PHARMACOTHERAPY, 2023, 24 (17) : 1833 - 1837
[40] Rogaratinib: A potent and selective pan-FGFR inhibitor with broad antitumor activity in FGFR-overexpressing preclinical cancer models
Gruenewald, Sylvia
Politz, Oliver
Bender, Sebastian
Heroult, Melanie
Lustig, Klemens
Thuss, Uwe
Kneip, Christoph
Kopitz, Charlotte
Zopf, Dieter
Collin, Marie-Pierre
Boemer, Ulf
Ince, Stuart
Ellinghaus, Peter
Mumberg, Dominik
Hess-Stumpp, Holger
Ziegelbauer, Karl
INTERNATIONAL JOURNAL OF CANCER, 2019, 145 (05) : 1346 - 1357

← 1 2 3 4 5 →