Inhibition of Neisseria gonorrhoeae by Lactobacillus species that are commonly isolated from the female genital tract

被引:50
|
作者
Amant, DCS [1 ]
Valentin-Bon, IE [1 ]
Jerse, AE [1 ]
机构
[1] Uniformed Serv Univ Hlth Sci, Dept Microbiol & Immunol, F Edward Hebert Sch Med, Bethesda, MD 20814 USA
关键词
D O I
10.1128/IAI.70.12.7169-7171.2002
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Epidemiological studies suggest H2O2-producing lactobacilli protect women against gonorrhea. Here we demonstrate that Lactobacillus crispatus and Lactobacillus jensenii, the most common lactobacilli in the female genital tract, inhibit gonococci in both acidic and neutral pH conditions. Inhibition was neutralized by bovine catalase, suggesting that H2O2 is the primary mediator of inhibition.
引用
收藏
页码:7169 / 7171
页数:3
相关论文
共 50 条
  • [41] COLONIAL MORPHOLOGY OF NEISSERIA GONORRHOEAE ISOLATED FROM MALES AND FEMALES
    SPARLING, PF
    YOBS, AR
    JOURNAL OF BACTERIOLOGY, 1967, 93 (01) : 513 - &
  • [42] Anion inhibition studies of the α-carbonic anhydrases from Neisseria gonorrhoeae
    Nocentini, Alessio
    Hewitt, Chad S.
    Mastrolorenzo, Margaret D.
    Flaherty, Daniel P.
    Supuran, Claudiu T.
    JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, 2021, 36 (01) : 1061 - 1066
  • [43] Chlamydia trachomatis, Neisseria gonorrhoeae and human papillomavirus infections of lower genital tract of Indigenous women from Xingu Indigenous Park
    Porto, Claudia Regina Cinti Correa
    Longatto-Filho, Adhemar
    De Almeida, Bruna Cristine
    Bonetti, Tatiana C. S.
    Kamaiura, Sula Fernanda A.
    Diaz, Ricardo Sobhie
    Heinke, Thais
    Cury, Fernanda de Paula
    Santana, Iara Viana Vidigal
    Queiroz, Mariana M.
    Rodrigues, Douglas Antonio
    Speck, Neila Maria De Gois
    RURAL AND REMOTE HEALTH, 2023, 23 (03):
  • [44] CHARACTERIZATION AND INHIBITION OF DIHYDROFOLATE SYNTHETASE FROM NEISSERIA-GONORRHOEAE
    PONGSAMART, S
    HO, RI
    CORMAN, L
    FOYE, WO
    MOLECULAR AND CELLULAR BIOCHEMISTRY, 1984, 59 (1-2) : 165 - 171
  • [45] A DNA-SEQUENCE FOR THE DISCRIMINATION OF NEISSERIA-GONORRHOEAE FROM OTHER NEISSERIA SPECIES
    MIYADA, CG
    BORN, TL
    MOLECULAR AND CELLULAR PROBES, 1991, 5 (05) : 327 - 335
  • [46] Lactobacillus isalae sp. nov., isolated from the female reproductive tract
    Eilers, Tom
    Dillen, Jelle
    Ahannach, Sarah
    Vander Donck, Leonore
    Van de Vliet, Nele
    Wittouck, Stijn
    Lebeer, Sarah
    INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY, 2023, 73 (10)
  • [47] Female genital-tract HIV load correlates inversely with Lactobacillus species but positively with bacterial vaginosis and Mycoplasma hominis
    Sha, BE
    Zariffard, MR
    Wang, QJ
    Chen, HY
    Bremer, J
    Cohen, MH
    Spear, GT
    JOURNAL OF INFECTIOUS DISEASES, 2005, 191 (01): : 25 - 32
  • [48] Draft genome sequences of Lactobacillus paragasseri strains isolated from the female urinary tract
    Jackson, Briana
    Stegman, Natalie
    Sedano, Cerena
    Steiling, Maria
    Putonti, Catherine
    MICROBIOLOGY RESOURCE ANNOUNCEMENTS, 2024, 13 (02):
  • [49] Draft genome sequences of Lactobacillus mulieris strains isolated from the female urinary tract
    Stegman, Natalie
    Steiling, Maria
    Sedano, Cerena
    Jackson, Briana
    Putonti, Catherine
    MICROBIOLOGY RESOURCE ANNOUNCEMENTS, 2024, 13 (02):
  • [50] BETTER SPECIMENS FROM FEMALE GENITAL TRACT
    HUGHES, WH
    DAVIES, JM
    BRITISH MEDICAL JOURNAL, 1971, 4 (5784): : 424 - &