Neomycin production with free and immobilized cells of Streptomyces marinensis in an airlift reactor

被引：44

作者：

Srinivasulu, B

Prakasham, RS ^{[1
]}

Jetty, A

Srinivas, S

Ellaiah, P

Ramakrishna, SV

机构：

[1] Indian Inst Chem Technol, Biochem & Environm Engn Ctr, Hyderabad 500007, Andhra Pradesh, India

[2] Andhra Univ, Dept Pharmaceut Sci, Waltair 530003, Andhra Pradesh, India

来源：

PROCESS BIOCHEMISTRY | 2002年 / 38卷 / 04期

关键词：

bioreactor; immobilization; neomycin; Streptomyces marinensis;

D O I：

10.1016/S0032-9592(02)00182-6

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Neomycin production by free and alginate immobilized Streptomyces marinensis cells was investigated in an airlift reactor. Neomycin production was increased two and a half times with immobilized cells. A marginal decrease in neomycin production was noticed with reduced supplementation of carbon source (up to one-fourth concentration). Immobilized S. marinensis particles showed a half-life of 20 days during continuous fermentation in an airlift reactor. (C) 2002 Elsevier Science Ltd. All rights reserved.

引用

页码：593 / 598

页数：6

共 50 条

[1] Continuous neomycin production by immobilized cells of Streptomyces marinensis NUV-5 in an airlift bioreactor
Adinarayana, K
Srinivasulu, B
Raju, KVVSNB
Ellaiah, P
PROCESS BIOCHEMISTRY, 2004, 39 (11) : 1407 - 1414
[2] STRAIN IMPROVEMENT STUDIES FOR NEOMYCIN PRODUCTION BY STREPTOMYCES-MARINENSIS
ELLAIAH, P
MURTHY, PVK
INDIAN JOURNAL OF EXPERIMENTAL BIOLOGY, 1988, 26 (07) : 562 - 563
[3] Studies on neomycin production using immobilized cells ofS marinensis NUV-5 in various reactor configurations: A technical note
Bandi Srinivasulu
Poluri Ellaiah
Kunamneni Adinarayana
AAPS PharmSciTech, 4 (3)
[4] INFLUENCE OF AERATION LEVELS ON NEOMYCIN TITER IN CONTINUOUS STIRRED REACTOR BY STREPTOMYCES-MARINENSIS
ELLAIAH, P
BABU, MK
CURRENT SCIENCE, 1987, 56 (01): : 22 - 23
[5] Effect of magnetic field on the biosynthesis of neomycin by Streptomyces marinensis
Ellaiah, P
Adinarayana, K
Sunitha, M
PHARMAZIE, 2003, 58 (01): : 58 - 59
[6] Investigations on neomycin production with immobilized cells ofStreptomyces marinensis Nuv-5 in calcium alginate matrix
Bandi Srinivasulu
Kunamneni Adinarayana
Poluri Ellaiah
AAPS PharmSciTech, 4 (4)
[7] Optimisation studies on neomycin production by a mutant strain of Streptomyces marinensis in solid state fermentation
Ellaiah, P
Srinivasulu, B
Adinarayana, K
PROCESS BIOCHEMISTRY, 2004, 39 (05) : 529 - 534
[8] Improved production of Daptomycin in an airlift bioreactor by morphologically modified and immobilized cells of Streptomyces roseosporus
Ipsita Chakravarty
Subir Kundu
AMB Express, 6
[9] Improved production of Daptomycin in an airlift bioreactor by morphologically modified and immobilized cells of Streptomyces roseosporus
Chakravarty, Ipsita
Kundu, Subir
AMB EXPRESS, 2016, 6
[10] AN AIRLIFT LOOP REACTOR FOR THE TRANSFORMATION OF STEROIDS BY IMMOBILIZED CELLS
KLOOSTERMAN, J
LILLY, MD
BIOTECHNOLOGY LETTERS, 1985, 7 (01) : 25 - 30

← 1 2 3 4 5 →