[γ-Fe2O3@HAp-SO3H] an efficient nanocatalyst for the synthesis of highly functionalised 2-thioxopyrido[2,3-d]pyrimidines

被引：6

作者：

Mamaghani, Manouchehr ^{[1
,2
]}

Taati, Zahra ^{[1
]}

Rasoulian, Mona ^{[1
]}

Yousefizad, Javad ^{[2
]}

Toraji, Nooshin ^{[2
]}

Mohsenimehr, Mona ^{[1
]}

Nia, Roghayeh Hossein ^{[1
]}

机构：

[1] Univ Guilan, Fac Sci, Dept Chem, POB 41335-1914, Rasht, Iran

[2] Islamic Azad Univ, Fac Sci, Dept Chem, Rasht Branch, POB 41335-3516, Rasht, Iran

来源：

JOURNAL OF CHEMICAL RESEARCH | 2016年 / 01期

关键词：

nanocatalyst; magnetic nanoparticles; 2-thioxopyridopyrimidine; 6-aminothiouracil; cyanopyrido[2,3-d]pyrimidine-5-one; thioxodihydropyrimidine-4,6(1H,5H)-dione; ONE-POT SYNTHESIS; MAGNETICALLY SEPARABLE CATALYST; SULFONIC-ACID GROUPS; DERIVATIVES; 3,4-DIHYDROPYRIMIDIN-2(1H)-ONES; CONDENSATION; INHIBITORS; AGENTS; GREEN; WATER;

D O I：

10.3184/174751916X14495860660659

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

HAp(hydroxyapatite)-encapsulated-gamma-Fe2O3 supported sulfonic acid nanoparticles were used for the preparation of two series of 2-thioxopyrido[2,3-d]pyrimidines. In the first series, 2-thioxopyrido[2,3-d]pyrimidines were synthesised from 3-(6-amino-1,2,3,4-tetrahydro-4-oxo-2-thioxopyrimidin-5-yl)-3-oxopropanenitrile and arylaldehydes in the presence of [gamma-Fe2O3@HAp-SO3H] as a nanocatalyst, in high yields (84-96%). In the second series, [gamma-Fe2O3@HAp-SO3H] was used to catalyse the reaction of 6-amino-2-(alkylthio)-pyrimidine-4,6(1H,5H)-dione, 1,3-diethyl-2-thioxodihydropyrimidine-4,6(1H,5H)-dione and various arylaldehydes to prepare 2-thioxo-2,3,7,10-tetrahydropyrido[2,3-d:5,6-d'] dipyrimidine-4,6 (1H,5H)-diones in excellent yields (93-98%).

引用

页码：29 / 34

页数：6

共 50 条

[41] PYRIDO[2,3-D]PYRIMIDINES .8. SYNTHESIS OF PYRROLO(2',3'/4,5)PYRIDO[2,3-D]PIRIMIDINES
BISTRYAKOVA, ID
SMIRNOVA, NM
SAFONOVA, TS
KHIMIYA GETEROTSIKLICHESKIKH SOEDINENII, 1993, (06): : 800 - 803
[42] Synthesis and characterization of Fe3O4@THAM-SO3H as a highly reusable nanocatalyst and its application for the synthesis of dihydropyrano[2,3-c]pyrazole derivatives
Faroughi Niya, Homayoun
Hazeri, Nourallah
Maghsoodlou, Malek Taher
APPLIED ORGANOMETALLIC CHEMISTRY, 2020, 34 (04)
[43] Synthesis of substituted 3,4-dihydrofuro[2,3-d]pyrimidines from 3-arylmethylidenefuran-2(3H)-ones
T. V. Anis’kova
A. A. Verevochkin
A. Yu. Egorova
Russian Journal of Organic Chemistry, 2016, 52 : 1861 - 1862
[44] Synthesis of substituted 3,4-dihydrofuro[2,3-d]pyrimidines from 3-arylmethylidenefuran-2(3H)-ones
Anis'kova, T. V.
Verevochkin, A. A.
Egorova, A. Yu
RUSSIAN JOURNAL OF ORGANIC CHEMISTRY, 2016, 52 (12) : 1861 - 1862
[45] Synthesis and antihistaminic activity of 2-guanadino-3-cyanopyridines and pyrido[2,3-d]-pyrimidines
Quintela, JM
Peinador, C
Botana, L
Estevez, M
Riguera, R
BIOORGANIC & MEDICINAL CHEMISTRY, 1997, 5 (08) : 1543 - 1553
[46] Nano-sawdust-OSO3H as a new, cheap and effective nanocatalyst for one-pot synthesis of pyrano[2,3-d]pyrimidines
B. Sadeghi
M. Bouslik
M. R. Shishehbore
Journal of the Iranian Chemical Society, 2015, 12 : 1801 - 1808
[47] SYNTHESIS OF SOME PYRIDO[2,3-D]PYRIMIDINES
DAS, A
SAHU, K
MISHRA, BK
BEHERA, GB
INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY, 1985, 24 (03): : 310 - 311
[48] INVESTIGATIONS ON THE SYNTHESIS AND PROPERTIES OF ARYLPIPERAZINYLALKYL DERIVATIVES OF SOME DIHYDROPYRIDO[2,3-D]PYRIMIDINES AND TETRAHYDROPYRIDO[2,3-D]PYRIMIDINES
SLADOWSKA, H
FARMACO, 1993, 48 (01): : 77 - 84
[49] SYNTHESIS OF NOVEL 3,6-DISUBSTITUTED FURO[2,3-d]PYRIMIDINES
Bakavoli, Mehdi
Rahimizadeh, Mohammad
Gordi, Zinat
HETEROCYCLES, 2008, 75 (10) : 2549 - 2553
[50] SYNTHESIS OF NEW 3-CARBOXAMIDINE IMINOCOUMARINS AND BENZOPYRANO[2,3-d]PYRIMIDINES
Trichili, Sihem
Kammoun, Myriam
Turki-Guermazi, Hamida
Abid, Souhir
Ammar, Houcine
SYNTHETIC COMMUNICATIONS, 2015, 45 (08) : 958 - 966

← 1 2 3 4 5 →