Four New Fatty Acid Esters from the Feces of Trogopterus xanthipes

被引:12
|
作者
Yang, Nian-Yun [1 ]
Tao, Wei-Wei [1 ]
Duan, Jin-Ao [1 ]
Guo, Jian-Ming [1 ]
Cao, Ling-Ling [1 ]
机构
[1] Nanjing Univ Tradit Chinese Med, Jiangsu Key Lab TCM Formulae Res, Nanjing 210046, Peoples R China
关键词
Feces Trogopterus; Fatty acid ester; Antithrombin activity;
D O I
10.1007/s11745-009-3329-z
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Four new fatty acid esters have been isolated from Feces Trogopterus. Their structures were determined by spectroscopic and chemical methods to be bis(7-hydroxyheptyl) icosanedioate (1), bis(7-hydroxyheptyl) heptadecanedioate (2), bis(7-hydroxyheptyl) decanedioate (3), and bis(7-hydroxyheptyl) octanedioate (4). In the anticoagulative assay, compounds 3 and 4 had significant antithrombin activity.
引用
收藏
页码:849 / 853
页数:5
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