Synthesis of monodisperse poly(styrene-co-divinylbenzene) microspheres with binary porous structures and application in high-performance liquid chromatography

被引:35
|
作者
Yu, Bing [1 ,2 ]
Tian, Chao [1 ]
Cong, Hailin [1 ,2 ]
Xu, Tao [1 ]
机构
[1] Qingdao Univ, Coll Mat Sci & Engn, Qingdao 266071, Peoples R China
[2] Qingdao Univ, Coll Chem & Chem Engn, Growing Base State Key Lab, Lab New Fiber Mat & Modern Text, Qingdao 266071, Peoples R China
关键词
POLYSTYRENE MICROSPHERES; MACROPOROUS PARTICLES; AQUEOUS DISPERSIONS; PHASE; BEADS; UNIFORM; MEDIA; POLYMERIZATION; MORPHOLOGY; SEPARATION;
D O I
10.1007/s10853-016-9826-6
中图分类号
T [工业技术];
学科分类号
08 ;
摘要
Monodisperse poly(styrene-co-divinylbenzene) (PS-DVB) microspheres with binary porous structures were synthesized using a modified seeded polymerization method. The microspheres had small pores on the surface and big pores in the middle. Using the binary porous PS-DVB (BPPSD) microspheres as packing materials for high-performance liquid chromatography, several benzene analogs were effectively separated in a column as short as 75 mm due to the high surface areas of the stationary phase. Because of the pi-pi affinity interaction between BPPSD particles and analytes, the separation performance of the BPPSD column was better than commercialized C-18 column at the same conditions. Compared to column filled with non-porous PS-DVB particles, the back pressure of BPPSD column could be maintained at especially low level even at high flow rates due to the excellent permeability of the fillers. In addition, approximate baseline separation of C-60 and C-70 was also achieved in the 75 mm BPPSD column.
引用
收藏
页码:5240 / 5251
页数:12
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