HEXABODY-CD27 ENHANCES T-CELL ACTIVATION, PROLIFERATION, CYTOKINE SECRETION AND CYTOTOXIC ACTIVITY INDEPENDENTLY OF FC GAMMA RECEPTOR-MEDIATED CROSSLINKING

被引：0

作者：

Nurmberger, Kristina ^{[2
]}

Imle, Andrea ^{[2
]}

Toker, Aras ^{[2
]}

Strumane, Kristin ^{[1
]}

Fellermeier-Kopf, Sina ^{[2
]}

Ioan-Facsinay, Andreea ^{[1
]}

Muik, Alexander ^{[2
]}

Diken, Mustafa ^{[2
]}

Beurskens, Frank ^{[1
]}

De Jong, Rob ^{[1
]}

Kreiter, Sebastian ^{[2
]}

Satijn, David ^{[1
]}

Gieseke, Friederike ^{[2
]}

Schuurman, Janine ^{[1
]}

Ahmadi, Tahamtam

Tuereci, Oezlem ^{[2
]}

Sasser, Kate ^{[3
]}

Breij, Esther ^{[1
]}

Sahin, Ugur ^{[2
]}

Altinas, Isil ^{[1
]}

机构：

[1] Genmab BV, Utrecht, Netherlands

[2] BioNTech SE, Mainz, Germany

[3] Genmab US Inc, Plainsboro, NJ USA

来源：

JOURNAL FOR IMMUNOTHERAPY OF CANCER | 2022年 / 10卷

关键词：

D O I：

10.1136/jitc-2022-SITC2022.1070

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

1070

引用

页码：A1112 / A1112

页数：1

共 29 条

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[23] INHIBITION OF INTERFERON-GAMMA-MEDIATED IMMUNE FUNCTIONS BY OLIGONUCLEOTIDES - SUPPRESSION OF HUMAN T-CELL PROLIFERATION BY DOWN-REGULATION OF IFN-GAMMA-INDUCED ICAM-1 AND FC-RECEPTOR ON ACCESSORY CELLS
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[25] THE HEPATITIS C VIRUS ENHANCES ACTIVATION OF THE EGF-RECEPTOR AND AKT-ACTIVITY BY NS3/4A-MEDIATED CLEAVAGE OF THE T-CELL PROTEIN TYROSINE PHOSPHATASE
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[26] A NOVEL ACTIVATION PATHWAY FOR MATURE THYMOCYTES - COSTIMULATION OF CD2 (T,P50) AND CD28 (T,P44) INDUCES AUTOCRINE INTERLEUKIN-2 INTERLEUKIN-2 RECEPTOR-MEDIATED CELL-PROLIFERATION
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[28] CD69-MEDIATED PATHWAY OF LYMPHOCYTE-ACTIVATION - ANTI-CD69 MONOCLONAL-ANTIBODIES TRIGGER THE CYTOLYTIC ACTIVITY OF DIFFERENT LYMPHOID EFFECTOR-CELLS WITH THE EXCEPTION OF CYTOLYTIC LYMPHOCYTES-T EXPRESSING T-CELL RECEPTOR-ALPHA/BETA
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[29] RESPONSIVENESS FOR MOUSE IGG2B ANTIBODIES TO THE HUMAN ALPHA/BETA T-CELL RECEPTOR CD3 COMPLEX - EVIDENCE FOR GENETIC DETERMINATION AND LOW-GRADE ANTIBODY CROSS-LINKING NOT MEDIATED BY KNOWN FC-GAMMA RECEPTORS
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