Mechanical property and biocompatibility of co-precipitated nano hydroxyapatite-gelatine composites

被引：13

作者：

Le, Huirong ^{[1
]}

Natesan, Kiruthika ^{[2
,3
]}

Pranti-Haran, Sundaram ^{[4
]}

机构：

[1] Univ Plymouth, Sch Marine Sci & Engn, Plymouth PL4 8AA, Devon, England

[2] Univ Plymouth, Peninsular Sch Med, Plymouth PL4 8AA, Devon, England

[3] Univ Plymouth, Peninsular Sch Dent, Plymouth PL4 8AA, Devon, England

[4] Univ Dundee, Sch Engn Phys & Math, Dundee DD1 4HN, Scotland

来源：

JOURNAL OF ADVANCED CERAMICS | 2015年 / 4卷 / 03期

关键词：

biomaterials; nanocomposites; hydroxyapatite (HA); gelatine; biocompatibility; SELF-ORGANIZATION MECHANISM; COLLAGEN; NANOCOMPOSITES; RESPONSES; SURFACTANT; MORPHOLOGY; SCAFFOLDS; COATINGS;

D O I：

10.1007/s40145-015-0155-z

中图分类号：

TQ174 [陶瓷工业]; TB3 [工程材料学];

学科分类号：

0805 ; 080502 ;

摘要：

Uniform and well dispersed nano hydroxyapatite (HA)-gelatine composites were obtained by co-precipitation of hydroxyapatite and denatured calf skin collagen. The process allowed much higher concentration of hydroxyapatite to be produced over conventional hydrothermal process to improve the productivity. The effect of gelatine on the morphology, mechanical properties, and biocompatibility of hydroxyapatite particles was investigated. Fibroblast cell tests of the consolidated hydroxyapatite-gelatine composites showed that the composites have excellent biocompatibility.

引用

页码：237 / 243

页数：7

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