5-Methyl 3-(2-methylprop-3-yl) 2,6-dimethyl-4-(2-nitrosophenyl)pyridine-3,5-dicarboxylate

被引:2
|
作者
Chen, Hui [1 ]
Qu, Ding [1 ]
Wang, Qiao-Feng [1 ]
Jiang, Ru [1 ]
机构
[1] Fourth Mil Med Univ, Sch Pharm, Xian 710032, Peoples R China
关键词
Data-to-parameter ratio = 14.5; Mean σ(C-C) = 0.005 Å; R factor = 0.077; Single-crystal X-ray study; T = 296 K; WR factor = 0.311;
D O I
10.1107/S1600536810005088
中图分类号
O7 [晶体学];
学科分类号
0702 ; 070205 ; 0703 ; 080501 ;
摘要
In the title compound, C20H22N2O5, a photo-degradation product of the hypertension drug nisoldipine, the dihedral angle between the nitrosophenyl ring and the pyridine ring is 75.7 (3)degrees. In the crystal structure, weak C-H center dot center dot center dot O hydrogen bonds help to establish the packing.
引用
收藏
页码:O619 / U5041
页数:9
相关论文
共 50 条
  • [41] 3-Methyl 5-{3-[(4-Methylbenzenesulfonyl)oxy]propyl} 4-(2,3-Dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
    Borgarelli, Carlotta
    Lenaers, Stijn
    De Borggraeve, Wim M.
    Ismalaj, Ermal
    MOLBANK, 2022, 2022 (04)
  • [42] Diisopropyl 1-(4-methoxyphenyl)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
    Kapoor, Kamini
    Gupta, Vivek K.
    Kant, Rajni
    Pawar, Milind P.
    Joshi, Hitendra S.
    ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2011, 67 : O2979 - U874
  • [43] STRUCTURE OF DIETHYL 2,6-DIMETHYL-4-[5-(4-METHYLPHENYL)-2-FURYL]-1,4-DIHYDROPYRIDINE-3,5-DICARBOXYLATE
    LOKAJ, J
    VRABEL, V
    SIVY, P
    KETTMANN, V
    ILAVSKY, D
    JECNY, J
    ACTA CRYSTALLOGRAPHICA SECTION C-STRUCTURAL CHEMISTRY, 1991, 47 : 886 - 888
  • [44] 3-Ethyl 5-methyl 2-hydroxy-6-methyl-4(4-nitrophenyl)-2-trifluoromethyl-1,2,3,4-tetrahydropyridine-3,5-dicarboxylate
    Yu, Chen-Xia
    Qian, Pei-Li
    Ping, Jia-Jing
    Yao, Chang-Sheng
    ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2008, 64 : O1737 - U1744
  • [45] Dimethyl 4-(3-hydroxyphenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
    Rajesh, K.
    Vijayakumar, V.
    Narasimhamurthy, T.
    Suresh, J.
    Tiekink, Edward R. T.
    ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2010, 66 : O985 - U3586
  • [46] Dimethyl 2,6-dimethyl-4-(3-phenyl-1Hpyrazol-4- yl)-1,4- dihydropyridine-3,5dicarboxylate
    Fun, Hoong-Kun
    Arshad, Suhana
    Malladi, Shridhar
    Shivananda, Kammasandra Nanjunda
    Isloor, Arun M.
    ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2012, 68 : O922 - +
  • [47] 3,5-dimethyl 2,6-dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate Effect on Induced Contractions by Hydrogen Peroxide on Trachea Smooth Muscle
    Borza, Claudia
    Motoc, Marilena
    REVISTA DE CHIMIE, 2012, 63 (12): : 1286 - 1288
  • [48] Solid-state photodimerization of methyl (RS)-1-phenyl-2-piperidinoethyl (RS)-1,4-dihydro-2,6-dimethyl-4-(2-thiazolyl)pyridine-3,5-dicarboxylate hydrochloride controlled by the buffer zone
    Marubayashi, N
    Ogawa, T
    Hirayama, N
    BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN, 1998, 71 (02) : 321 - 327
  • [49] INVITRO AND EXVIVO CA-ANTAGONISTIC EFFECT OF 2-METHOXYETHYL(E)-3-PHENYL-2-PROPEN-1-YL(+/-)-1,4-DIHYDRO-2,6-DIMETHYL-4-(3-NITROPHENYL)PYRIDINE-3,5-DICARBOXYLATE (FRC-8653), A NEW DIHYDROPYRIDINE DERIVATIVE
    HOSONO, M
    IIDA, H
    IKEDA, K
    HAYASHI, Y
    DOHMOTO, H
    HASHIGUCHI, Y
    YAMAMOTO, H
    WATANABE, N
    YOSHIMOTO, R
    JOURNAL OF PHARMACOBIO-DYNAMICS, 1992, 15 (10): : 547 - 553
  • [50] Synthesis and biological activity of the calcium modulator (R) and (S)-3-methyl 5-pentyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
    Zhang, Bang-le
    He, Wei
    Shi, Xin
    Huan, Meng-lei
    Huang, Qiu-ju
    Zhou, Si-yuan
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2010, 20 (03) : 805 - 808