Chemoenzymatic dynamic kinetic resolution of secondary amines

被引：93
|
作者：
Stirling, Matthew
Blacker, John
Page, Michael I. [1 ]
机构：
[1] Univ Huddersfield, Dept Chem & Biol Sci, Huddersfield HD1 3DH, W Yorkshire, England
[2] NPILPharma, Huddersfield HD1 9GA, W Yorkshire, England
来源：
TETRAHEDRON LETTERS | 2007年 / 48卷 / 07期
关键词：
D O I：
10.1016/j.tetlet.2006.12.032
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The kinetic resolution of amines using a novel iridium based catalyst coupled with an enzyme catalysed step is achieved on a large scale with high yields and ee. (c) 2006 Elsevier Ltd. All rights reserved.
引用
收藏
页码：1247 / 1250
页数：4
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