Synthesis of Spiranes by Thiol-Mediated Acyl Radical Cyclization

被引：20
|
作者：
Hsu, Day-Shin [1 ]
Chen, Chih-Hao [1 ]
Hsu, Chi-Wei [1 ]
机构：
[1] Natl Chung Cheng Univ, Dept Chem & Biochem, Minhsiung 621, Taiwan
来源：
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY | 2016年 / 2016卷 / 03期
关键词：
Synthetic methods; Cyclization; Radical reactions; Spiro compounds; Acyl radicals; Acylation; CARBOCYCLIC SPIRO COMPOUNDS; OXIDATION;
D O I：
10.1002/ejoc.201501305
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A general and efficient method for the preparation of spiro compounds is described. Various enone-aldehydes were exposed to t-dodecanethiol and AIBN at 75 degrees C in toluene to afford spirocyclic 1,4-diketones in moderate to good yields.
引用
收藏
页码：589 / 598
页数：10
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