Non-Invasive Evaluation of Hepatic Fibrosis for Type C Chronic Hepatitis

被引：89
|
作者：
Tatsumi, Chie [1 ]
Kudo, Masatoshi [1 ]
Ueshima, Kazuomi [1 ]
Kitai, Satoshi [1 ]
Ishikawa, Emi [1 ]
Yada, Norihisa [1 ]
Hagiwara, Satoru [1 ]
Inoue, Tatsuo [1 ]
Minami, Yasunori [1 ]
Chung, Hobyung [1 ]
Maekawa, Kiyoshi [2 ]
Fujimoto, Kenji [3 ]
Kato, Michio [3 ]
Tonomura, Akiko [4 ]
Mitake, Tsuyoshi [4 ]
Shiina, Tsuyoshi [5 ]
机构：
[1] Kinki Univ, Sch Med, Dept Gastroenterol & Hepatol, Osaka 589, Japan
[2] Kinki Univ, Sch Med, Dept Lab Med, Div Abdominal Ultrasound, Osaka 589, Japan
[3] Natl Hosp Org Minami Wakayama Med Ctr, Dept Internal Med, Tanabe, Japan
[4] Hitachi Med Corp, Tokyo, Japan
[5] Kyoto Univ, Grad Sch Med, Kyoto, Japan
来源：
INTERVIROLOGY | 2010年 / 53卷 / 01期
关键词：
Biopsy; liver; FibroScan; Fibrosis; Real-time tissue elastography; TRANSIENT ELASTOGRAPHY; DIAGNOSIS; DISEASE;
D O I：
10.1159/000252789
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
Objective: The aim of this study was to investigate liver fibrosis using non-invasive Real-time Tissue Elastography(R) (RTE) and transient elastography (FibroScan(R)) methods. Methods: RTE, FibroScan and percutaneous liver biopsy were all performed on patients with chronic liver disease, particularly hepatitis C, to investigate liver fibrosis. Results: FibroScan and RTE were compared for fibrous liver staging (F stage), which was pathologically classified using liver biopsy. In FibroScan, significant differences were observed between F1/F3 and F2/F4, but no such differences were observed between F1/F2, F2/F3 and F3/F4. In RTE, significant differences were observed between F1/F2, F2/F3 and F2/F4. But for F3/F4, no significant differences were observed. Conclusion: FibroScan and RTE correlated well with F staging of the liver. In particular RTE was more successful than FibroScan in diagnosing the degree of liver fibrosis. Copyright (C) 2010 S. Karger AG, Basel
引用
收藏
页码：76 / 81
页数：6
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