Non-Invasive Evaluation of Hepatic Fibrosis for Type C Chronic Hepatitis

被引：89

作者：

Tatsumi, Chie ^{[1
]}

Kudo, Masatoshi ^{[1
]}

Ueshima, Kazuomi ^{[1
]}

Kitai, Satoshi ^{[1
]}

Ishikawa, Emi ^{[1
]}

Yada, Norihisa ^{[1
]}

Hagiwara, Satoru ^{[1
]}

Inoue, Tatsuo ^{[1
]}

Minami, Yasunori ^{[1
]}

Chung, Hobyung ^{[1
]}

Maekawa, Kiyoshi ^{[2
]}

Fujimoto, Kenji ^{[3
]}

Kato, Michio ^{[3
]}

Tonomura, Akiko ^{[4
]}

Mitake, Tsuyoshi ^{[4
]}

Shiina, Tsuyoshi ^{[5
]}

机构：

[1] Kinki Univ, Sch Med, Dept Gastroenterol & Hepatol, Osaka 589, Japan

[2] Kinki Univ, Sch Med, Dept Lab Med, Div Abdominal Ultrasound, Osaka 589, Japan

[3] Natl Hosp Org Minami Wakayama Med Ctr, Dept Internal Med, Tanabe, Japan

[4] Hitachi Med Corp, Tokyo, Japan

[5] Kyoto Univ, Grad Sch Med, Kyoto, Japan

来源：

INTERVIROLOGY | 2010年 / 53卷 / 01期

关键词：

Biopsy; liver; FibroScan; Fibrosis; Real-time tissue elastography; TRANSIENT ELASTOGRAPHY; DIAGNOSIS; DISEASE;

D O I：

10.1159/000252789

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Objective: The aim of this study was to investigate liver fibrosis using non-invasive Real-time Tissue Elastography(R) (RTE) and transient elastography (FibroScan(R)) methods. Methods: RTE, FibroScan and percutaneous liver biopsy were all performed on patients with chronic liver disease, particularly hepatitis C, to investigate liver fibrosis. Results: FibroScan and RTE were compared for fibrous liver staging (F stage), which was pathologically classified using liver biopsy. In FibroScan, significant differences were observed between F1/F3 and F2/F4, but no such differences were observed between F1/F2, F2/F3 and F3/F4. In RTE, significant differences were observed between F1/F2, F2/F3 and F2/F4. But for F3/F4, no significant differences were observed. Conclusion: FibroScan and RTE correlated well with F staging of the liver. In particular RTE was more successful than FibroScan in diagnosing the degree of liver fibrosis. Copyright (C) 2010 S. Karger AG, Basel

引用

页码：76 / 81

页数：6

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