Unravelling Allosteric Cross-Talk between Co-Activator Peptide and Ligand Binding Site in Glucocorticoid Receptor

被引:0
|
作者
La Sala, Giuseppina [1 ]
Gunnarsson, Anders [2 ]
Edman, Karl [2 ]
Tyrchan, Christian [3 ]
Hogner, Anders [1 ]
Frolov, Andrey [1 ]
机构
[1] AstraZeneca, Med Chem Res & Early Dev, CVRM, BioPharmaceut R&D, Gothenburg, Sweden
[2] AstraZeneca, Discovery Sci, BioPharmaceut R&D, Gothenburg, Sweden
[3] AstraZeneca, Med Chem Res & Early Dev, BioPharmaceut R&D, R&I, Gothenburg, Sweden
关键词
D O I
暂无
中图分类号
Q6 [生物物理学];
学科分类号
071011 ;
摘要
1434-Pos
引用
收藏
页码:298A / 298A
页数:1
相关论文
共 50 条
  • [31] Cross-Talk of Receptor Activator of Nuclear Factor-κB Ligand Signaling With Renin-Angiotensin System in Vascular Calcification
    Osako, Mariana Kiomy
    Nakagami, Hironori
    Shimamura, Munehisa
    Koriyama, Hiroshi
    Nakagami, Futoshi
    Shimizu, Hideo
    Miyake, Takashi
    Yoshizumi, Masao
    Rakugi, Hiromi
    Morishita, Ryuichi
    ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2013, 33 (06) : 1287 - +
  • [32] Cross-talk between an activator of nuclear receptors-mediated transcription and the D1 dopamine receptor signaling pathway
    Schmidt, A
    Vogel, R
    Rutledge, SJ
    Opas, EE
    Rodan, GA
    Friedman, E
    PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR, 2005, 80 (03) : 379 - 385
  • [33] A Cross-Talk Between Motilin Receptor and Growth Hormone Secretagogue Receptor Using Chimeric Constructs' Expression and Co-Expression
    Matsuura, Bunzo
    Utsunomiya, Sachiko
    Ueda, Teruhisa
    Miyake, Teruki
    Furukawa, Shinya
    Murakami, Hidehiro
    Abe, Masanori
    Hiasa, Yoichi
    Onji, Morikazu
    GASTROENTEROLOGY, 2010, 138 (05) : S256 - S256
  • [34] Identification and Characterization of Multiple Similar Ligand-binding Repeats in Filamin IMPLICATION ON FILAMIN-MEDIATED RECEPTOR CLUSTERING AND CROSS-TALK
    Ithychanda, Sujay Subbayya
    Hsu, Dennis
    Li, Hanhan
    Yan, Linda
    Liu, Darwen
    Das, Mitali
    Plow, Edward F.
    Qin, Jun
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2009, 284 (50) : 35113 - 35121
  • [35] Cross-talk between thyroid hormone and specific retinoid X receptor subtypes in yeast selectively regulates cognate ligand actions
    Walfish, PG
    Yang, YF
    Yoganathan, T
    Chang, LA
    Butt, TR
    GENE EXPRESSION, 1996, 6 (03): : 169 - 184
  • [36] RARβ ligand-binding domain bound to an SRC-1 co-activator peptide:: purification, crystallization and preliminary X-ray diffraction analysis
    Kammerer, S
    Germain, P
    Flaig, R
    Peluso-Iltis, C
    Mitschler, A
    Rochel, N
    Gronemeyer, H
    Moras, D
    ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY, 2004, 60 : 2048 - 2050
  • [37] Genome-Wide Mapping of Estrogen Receptor-β-Binding Regions Reveals Extensive Cross-Talk with Transcription Factor Activator Protein-1
    Zhao, Chunyan
    Gao, Hui
    Liu, Yawen
    Papoutsi, Zoi
    Jaffrey, Sadaf
    Gustafsson, Jan-Ake
    Dahlman-Wright, Karin
    CANCER RESEARCH, 2010, 70 (12) : 5174 - 5183
  • [38] Targeting the cross-talk between Urokinase receptor and Formyl peptide receptor type 1 to prevent invasion and trans-endothelial migration of melanoma cells
    Ragone, Concetta
    Minopoli, Michele
    Ingangi, Vincenzo
    Botti, Giovanni
    Fratangelo, Federica
    Pessi, Antonello
    Stoppelli, Maria Patrizia
    Ascierto, Paolo Antonio
    Ciliberto, Gennaro
    Motti, Maria Letizia
    Carriero, Maria Vincenza
    JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, 2017, 36
  • [39] Targeting the cross-talk between Urokinase receptor and Formyl peptide receptor type 1 to prevent invasion and trans-endothelial migration of melanoma cells
    Concetta Ragone
    Michele Minopoli
    Vincenzo Ingangi
    Giovanni Botti
    Federica Fratangelo
    Antonello Pessi
    Maria Patrizia Stoppelli
    Paolo Antonio Ascierto
    Gennaro Ciliberto
    Maria Letizia Motti
    Maria Vincenza Carriero
    Journal of Experimental & Clinical Cancer Research, 36
  • [40] Cross-Talk Between the Octarepeat Domain and the Fifth Binding Site of Prion Protein Driven by the Interaction of Copper(II) with the N-terminus
    Di Natale, Giuseppe
    Turi, Ildiko
    Pappalardo, Giuseppe
    Sovago, Imre
    Rizzarelli, Enrico
    CHEMISTRY-A EUROPEAN JOURNAL, 2015, 21 (10) : 4071 - 4084