Enantioselective Friedel-Crafts reaction of electron-rich alkenes catalyzed by chiral bronsted acid

被引：304
|
作者：
Terada, Masahiro [1 ]
Sorimachi, Keiichi [1 ]
机构：
[1] Tohoku Univ, Grad Sch Sci, Dept Chem, Sendai, Miyagi 9808578, Japan
来源：
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2007年 / 129卷 / 02期
关键词：
D O I：
10.1021/ja0678166
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
We present the first enantioselective catalysis of the Friedel-Crafts reaction via activation of electronrich multiple bonds by a chiral Br nsted acid. The reaction of various indole derivatives with a broad range of substituted enecarbamates affords the corresponding Friedel-Crafts products in high yield and enantioselectivity.
引用
收藏
页码：292 / 293
页数：2
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