Host-reactive donor CD8+T memory stem cells but not mature T memory cells primed against leukemic cells mediate potent graft-versus-leukemia effect.

被引：0
|
作者：
Hexner, Elizabeth O.
Frank, Dale
Emerson, Stephen G.
Zhang, Yi
机构：
[1] Univ Penn, Sch Med, Dept Med & Pediat, Philadelphia, PA 19104 USA
[2] Univ Penn, Sch Med, Dept Pathol, Philadelphia, PA 19104 USA
来源：
BLOOD | 2006年 / 108卷 / 11期
关键词：
D O I：
10.1182/blood.V108.11.190.190
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
190
引用
收藏
页码：60A / 60A
页数：1
相关论文
共 50 条
  • [21] CD25+CD4+T cells contribute to the control of memory CD8+T cells
    Murakami, M
    Sakamoto, A
    Bender, J
    Kappler, J
    Marrack, P
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2002, 99 (13) : 8832 - 8837
  • [22] Differential gene expression in memory CD8+T cells
    Schluns, KS
    Lefrancois, L
    FASEB JOURNAL, 1999, 13 (05): : A938 - A938
  • [23] The generation of heterogeneity in effector and memory CD8+T cells
    Charbonneau, T
    Dutton, R
    FASEB JOURNAL, 2003, 17 (07): : C84 - C84
  • [24] Differences between graft-versus-leukemia and graft-versus-host reactivity .1. Interaction of donor immune T cells with tumor and/or host cells
    Rocha, M
    Umansky, V
    Lee, KH
    Hacker, HJ
    Benner, A
    Schirrmacher, V
    BLOOD, 1997, 89 (06) : 2189 - 2202
  • [25] Donor γδT cells promote graft-versus-leukemia effect and ameliorate acute graft-versus-host disease in allogeneic hematopoietic stem cell transplantation
    Song Yuan
    Hu Bo
    Zhu Ying
    Liu Haiyan
    JOURNAL OF IMMUNOLOGY, 2016, 196
  • [26] CD4-CD8- regulatory T cells implicated in preventing graft-versus-host and promoting graft-versus-leukemia responses
    Young, KJ
    DuTemple, B
    Zhang, ZX
    Levy, G
    Zhang, L
    TRANSPLANTATION PROCEEDINGS, 2001, 33 (1-2) : 1762 - 1763
  • [27] Characterization of naive, memory and effector CD8+T cells: effect of age
    Gupta, S
    Bi, RF
    Su, K
    Yel, L
    Chiplunkar, S
    Gollapudi, S
    EXPERIMENTAL GERONTOLOGY, 2004, 39 (04) : 545 - 550
  • [28] Donor CD8+ T cells mediate graft-versus-leukemia activity without clinical signs of graft-versus-host disease in recipients conditioned with anti-CD3 monoclonal antibody
    Zhang, Chunyan
    Lou, Jingwei
    Li, Nainong
    Todorov, Ivan
    Lin, Chia-Lei
    Cao, Yu-An
    Contag, Christopher H.
    Kandeel, Fouad
    Forman, Stephen
    Zeng, Defu
    JOURNAL OF IMMUNOLOGY, 2007, 178 (02): : 838 - 850
  • [29] ILγR negative CD8+T cells are polyfunctional effector memory cells
    Cumberbatch, NJ
    Atzberger, A
    McMichael, A
    Callan, M
    IMMUNOLOGY, 2005, 116 : 88 - 88
  • [30] T-helper cells: Their role in the pathogenesis of graft-versus-host disease and graft-versus-leukemia effect
    Bunjes, D
    Theobald, M
    Nierle, T
    Hertenstein, B
    Merk, B
    Stefanic, M
    Novotny, J
    Arnold, R
    Heimpel, H
    BONE MARROW AND PERIPHERAL STEM CELL TRANSPLANTATION: MEDICAL PROBLEMS IN THE POSTTRANSPLANTATION PHASE AND REHABILITATION STRATEGIES, 1996, : 38 - 65
12345