Iron-catalyzed C-H/N-H activation by triazole guidance: versatile alkyne annulation

被引：50

作者：

Cera, G. ^{[1
]}

Haven, T. ^{[1
]}

Ackermann, L. ^{[1
]}

机构：

[1] Georg August Univ, Inst Organ & Biomol Chem, Tammannstr 2, D-37077 Gottingen, Germany

来源：

CHEMICAL COMMUNICATIONS | 2017年 / 53卷 / 48期

基金：

欧洲研究理事会;

关键词：

BOND ACTIVATION; DIRECTING GROUP; OXIDATIVE CYCLOADDITION; DIRECT ARYLATIONS; ACID-DERIVATIVES; AROMATIC AMIDES; FUNCTIONALIZATION; BENZAMIDES; ISOQUINOLONE; ALKENES;

D O I：

10.1039/c7cc03376a

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Iron-catalyzed C-H/N-H functionalizations were achieved by the aid of modular triazole amides. The alkyne annulation allowed for the expedient synthesis of valuable isoquinolone scaffolds with high levels of chemo-, site- and regio-selectivities.

引用

页码：6460 / 6463

页数：4

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